Abstract: Invention relates to new platinum (IV) complexes with substantially increased antitumor efficacy; a process for preparing these new platinum (IV) complexes; a pharmaceutical composition and a final dosage form for oral administration of the new platinum (IV) complexes; and the use of the new platinum (IV) complex in a method to treat a tumor disease, preferably a heavy-to-treat cancer, most preferably pancreatic cancer, preferably by oral administration.
Type:
Grant
Filed:
September 5, 2019
Date of Patent:
July 8, 2025
Assignee:
VUAB PHARMA A.S.
Inventors:
Vladimír Kysilka, Jan Mengler, Miloš Mikoška
Abstract: The invention relates to a new platinum (IV) complex with substantially increased antitumor efficacy. The invention further discloses a process for preparing of said complex and a pharmaceutical composition for the therapy of tumor diseases containing said complex.
Type:
Grant
Filed:
September 3, 2014
Date of Patent:
July 10, 2018
Assignee:
Vuab Pharma A.S.
Inventors:
Vladimir Kysilka, Jen Mengler, Karel Havlovic, Petr Kacer, Libor Cerveny
Abstract: The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.
Type:
Grant
Filed:
June 8, 2006
Date of Patent:
January 18, 2011
Assignee:
Vuab Pharma A.S.
Inventors:
Vladimir Kysilka, Jan Mengler, Petr Kacer, Libor Cerveny
Abstract: The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy.
Type:
Grant
Filed:
April 9, 2005
Date of Patent:
October 20, 2009
Assignee:
Vuab Pharma A.S.
Inventors:
Vladimir Kysilka, Tomas Kalisz, Petr Kacer
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