Abstract: Compositions, methods, and processes are used in topical applications for human or animal skin. A combination of five (5) active ingredients: caffeine, trehalose, asparagus extract, ceramide 2 (2%) and a resurrection plant, Myrothamnus flabellifolia, extract are used in a topical formulation, such as a cream, lotion, spray or gel to boost or activate autophagy, the body's innate processes for repairing cell damage. The five active ingredients are combined in different formulations to provide at least six (6) products for topical application, including, but not limited to, a cleanser, a spray essence, a day cream, a night cream, a serum and a booster. The five (5) active ingredients provide a unique biological composition, hereinafter called, “autophagy activating complex,” that changes the way skin ages, restores and renews radiance.