Patents Assigned to WAKAMONO CORPORATION
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Patent number: 11583498Abstract: The invention relates to a process for producing a Tan IIA nanoliposome system for foods and medical products, comprises: (i) preparing a dispersed phase by dissolving Tan IIA in ethanol in a Tan IIA weight:ethanol volume ratio of 8:10 by a stirrer at 300-500 rpm with heating to 40-60° C. within 4-8 hours; (ii) preparing a liposome carrier consisting of lecithin and olive oil in a ratio of 1:3 by weight by mixing in a constant temperature bath at 40-60° C. to ensure that lecithin is completely dissolved in the oil while stirring; (iii) adding the carrier to the dispersed phase in a ratio of 40:60 by weight, further heating the carrier and dispersed phase mixture to 40-60° C. and stirring at 800-1000 rpm within 1 to 2 hours; (iv) cooling the resulting mixture to 25° C. and pumping the cooled mixture, using an ultrasonic atomizer nozzle at 60 Hz (10-20 ?m droplet size, 10 mL/min), into 1-1.5 L of distilled water (with the temperature of the distilled water at 25° C.Type: GrantFiled: December 18, 2020Date of Patent: February 21, 2023Assignee: WAKAMONO CORPORATIONInventors: Hong Ngoc Thi Dang, Nam Hai Lai
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Publication number: 20210379543Abstract: The present invention relates to a process of producing a nano-Tan IIA microemulsion system comprising the following steps: (i) preparing a dispersed phase by dissolving Tan IIA in ethanol solvent in a ratio of mass of Tan IIA:volume of ethanol solvent of 8:10; (ii) preparing a carrier by heating liquid PEG (polyethylene glycol) to 60-80° C.; (iii) adding the carrier to the dispersed phase in a mass ratio of 40:60 with further heating of the dispersed phase to 40-60° C.; (iv) elmusifying by heating until the temperature reaches 100° C., adding ACRYSOL K-140 to the mixture of the carrier and dispersed phase obtained in step (iii) in a mass ratio of 40:60 with further stirring at 500-700 rpm at about 100° C. under vacuum; and (v) filtering the product by injection through a nanofilter system before filling-packing.Type: ApplicationFiled: August 24, 2021Publication date: December 9, 2021Applicant: Wakamono CorporationInventors: Hong Ngoc Thi Dan, Nam Hai Lai
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Patent number: 10882012Abstract: The present invention relates to a process of producing a nano resveratrol microemulsion system includes: (i) preparing a dispersal phase by dissolving resveratrol in an ethanol solvent; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) accounted from 40 to 60% by mass of the mixture of PEG and water to a temperature ranging from 60 to 80° C., then adding zeolite catalyst (0.1-0.4% by mass of mixture of PEG and water), stirring evenly; (iii) adding the carrier to the dispersal phase (in a ratio by mass of 40:60), continuing heating the said dispersal phase to 100° C., stirring at a speed of 400 to 800 rpm; (iv) elmusifying as follows: when the temperature arrives at 100° C., adding Tween to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 40:60, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 100° C. to 130° C.Type: GrantFiled: July 8, 2019Date of Patent: January 5, 2021Assignee: WAKAMONO CORPORATIONInventor: Hong Ngoc Thi Dang
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Publication number: 20190351378Abstract: The present invention relates to a process of producing a nano Omega-3 microemulsion system includes: (i) preparing a dispersal phase by heating Omega-3 to a temperature from 40 to 60° C.; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) to a temperature ranging from 40 to 60° C., stirring evenly; (iii) adding the carrier to the dispersal phase in a ratio by mass of 3:1, continuing to keep the said dispersal phase at a temperature ranging from 40 to 60° C., stirring at a speed of 400 to 800 rpm in vacuum; (iv) emulsifying as follows: when the temperature arrives at 60° C., adding ACRYSOL K-140 to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 6:4, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 60 to 80° C., in vacuum, the reaction temperature is kept at a temperature ranging from 60 to 80° C.Type: ApplicationFiled: August 5, 2019Publication date: November 21, 2019Applicant: WAKAMONO CORPORATIONInventor: Hong Ngoc Thi Dang
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Publication number: 20190336922Abstract: The present invention relates to a process of producing a nano resveratrol microemulsion system includes: (i) preparing a dispersal phase by dissolving resveratrol in an ethanol solvent; (ii) preparing a carrier by heating a liquid PEG (polyethylene glycol) accounted from 40 to 60% by mass of the mixture of PEG and water to a temperature ranging from 60 to 80° C., then adding zeolite catalyst (0.1-0.4% by mass of mixture of PEG and water), stirring evenly; (iii) adding the carrier to the dispersal phase (in a ratio by mass of 40:60), continuing heating the said dispersal phase to 100° C., stirring at a speed of 400 to 800 rpm; (iv) elmusifying as follows: when the temperature arrives at 100° C., adding Tween to the mixture of the carrier and dispersal phase in step (iii) in a ratio by mass of 40:60, continuing to stir at a speed of 500 to 700 rpm, at a temperature of 100° C. to 130° C.Type: ApplicationFiled: July 8, 2019Publication date: November 7, 2019Applicant: WAKAMONO CORPORATIONInventor: Hong Ngoc Thi Dang