Patents Assigned to Wako Pure Chemical Industries
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Publication number: 20170137553Abstract: The present invention relates to: (1) a graft polymer that has a polyolefin (A) as the main chain, and a polymer (B) polymerized a dye (b) having a radical reactive functional group, in a side chain; (2) the graft polymer which is characterized in that the dye (b) having the radical reactive functional group is a cationic rhodamine derivative, a cationic triarylmethane-type dye derivative or a cationic cyanine-type dye derivative, having an ethylenically unsaturated group; (3) a colored resin consisting of the graft polymer; as well as (4) a method for producing the colored resin, which is characterized by mixing the polyolefin (A), the dye (b) having the radical reactive functional group, and the radical reaction initiator (C), and subjecting a radical reaction of the mixture; and the like.Type: ApplicationFiled: July 1, 2015Publication date: May 18, 2017Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., RHOMBIC CORPORATIONInventors: Tatsuhiko Kimura, Masayuki Tomida, Taeyeon Kim, Yosuke Suzuki, Masahiro Takano
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Publication number: 20170121760Abstract: The object of the present invention is to provide a novel primer for use in the detection of Mycobacterium avium (M. avium), and a method for detection of M. avium conveniently, rapidly and with high precision by using the primer. More specifically, disclosed are an oligonucleotide which comprises a part or an entire of the nucleotide sequence selected from SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:37, SEQ ID NO:38, SEQ ID NO:39, SEQ ID NO:40, SEQ ID NO:41, SEQ ID NO:42, SEQ ID NO:130, SEQ ID NO:131, SEQ ID NO:132, SEQ ID NO:133, SEQ ID NO:134, SEQ ID NO:135 and SEQ ID NO:136, or a part or an entire of the sequence complementary to the nucleotide sequence, and which is capable of hybridizing with the nucleotide sequence for a Mycobacterium avium gene; a primer and a probe for use in the detection of M. avium, which comprises the oligonucleoride; and a method for detection of M. avium using the primer and/or probe.Type: ApplicationFiled: December 21, 2016Publication date: May 4, 2017Applicant: Wako Pure Chemical Industries, Ltd.Inventor: Tomokazu ISHIKAWA
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Publication number: 20170122943Abstract: The invention provides a method for measuring CK-MB in a sample by reacting the sample with a first antibody against CK-MB, a second antibody against CK-MB which recognizes an epitope different from that recognized by the first antibody, and an anti-CK-B antibody which recognizes a region of the 1st to 100th amino acid from N-terminus of the amino acid sequence of the subunit B of creatine kinase (step 1); measuring an optical change generated by the reaction (step 2); and determining a quantity of CK-MB in the sample on the basis of the result obtained in the step 2 (step 3). The invention also provides a kit to be used in the method, and a method for avoiding influence of creatine kinase BB isozyme in measuring CK-MB, comprising treating a sample with the anti-CK-B antibody.Type: ApplicationFiled: April 13, 2015Publication date: May 4, 2017Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Kazuma HANAI, Shinichi ODAGAKI, Tsutomu MASUDA
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Patent number: 9638706Abstract: An external standard solution for use in the analysis of amino acid in plasma, containing, (1) at least one amino acid selected from the following components A, at a concentration of 0.0007 M to 0.49 M, and (2) (i) at least one amino acid selected from the following components B, at a concentration of 0.2 to 0.9 times of the lowest-concentration amino acid among the amino acids selected from components A, (ii) at least one amino acid selected from the following components C, at a concentration of 0.1 to 0.4 times of the lowest-concentration amino acid among amino acids selected from the components A, or (iii) at least one amino acid selected from the following components D, at a concentration of 0.05 to 0.Type: GrantFiled: July 19, 2012Date of Patent: May 2, 2017Assignees: WAKO PURE CHEMICAL INDUSTRIES, LTD., AJINOMOTO CO., INC.Inventors: Masako Hayakawa, Kazutaka Shimbo, Hiroo Yoshida
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Patent number: 9624535Abstract: The invention provides a method for converting non-methylated cytosine in a single-stranded DNA into uracil by a bisulfite reaction with a high conversion efficiency from non-methylated cytosine into uracil. The invention also provides a method for amplifying the single-stranded DNA in which non-methylated cytosine has been converted into uracil, as well as a method for detecting methylated cytosine in the single-stranded DNA.Type: GrantFiled: December 10, 2012Date of Patent: April 18, 2017Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Yukinobu Hayashida, Naoyuki Yamamoto
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Patent number: 9567647Abstract: The object of the present invention is to provide a novel primer for use in the detection of Mycobacterium avium (M. avium), and a method for detection of M. avium conveniently, rapidly and with high precision by using the primer. More specifically, disclosed are an oligonucleotide which comprises a part or an entire of the nucleotide sequence selected from SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:37, SEQ ID NO:38, SEQ ID NO:39, SEQ ID NO:40, SEQ ID NO:41, SEQ ID NO:42, SEQ ID NO:130, SEQ ID NO:131, SEQ ID NO:132, SEQ ID NO:133, SEQ ID NO:134, SEQ ID NO:135 and SEQ ID NO:136, or a part or an entire of the sequence complementary to the nucleotide sequence, and which is capable of hybridizing with the nucleotide sequence for a Mycobacterium avium gene; a primer and a probe for use in the detection of M. avium, which comprises the oligonucleotide; and a method for detection of M. avium using the primer and/or probe.Type: GrantFiled: November 16, 2007Date of Patent: February 14, 2017Assignee: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventor: Tomokazu Ishikawa
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Publication number: 20170040612Abstract: It is an object of the present invention to provide an electrode having superior charge-discharge capacity, even in the case of using an active material containing silicon.Type: ApplicationFiled: April 21, 2015Publication date: February 9, 2017Applicants: WAKO PURE CHEMICAL INDUSTRIES, LTD., TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Shinichi Komaba, Kiyofumi Yamagiwa, Shoko Aoki, Kuniaki Okamoto, Takahiro Kiyosu, Yasuyoshi Mori, Takatoshi Matsuura, Michihiko Sato
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Publication number: 20170015765Abstract: It is an object of the present invention to provide a cyanine-based coloring composition having higher heat resistance, as compared with a conventional coloring composition. The present invention relates to a compound represented by the following general formula (1), a polymer having a monomer unit derived from the compound, along with a coloring composition, a coloring composition for a color filter, and a colored resin comprising the above-described compound or the above-described polymer.Type: ApplicationFiled: March 5, 2015Publication date: January 19, 2017Applicant: Wako Pure Chemical Industries, Ltd.Inventors: Yukihiko SHIDA, Katsufumi SUZUKI, Tomoaki HORIE
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Patent number: 9500650Abstract: An object of the present invention is to provide a method for evaluating a differentiation status of cells using a culture supernatant of stem cells. Provided is “undifferentiation sugar chain marker” composed of the sugar chain structure “Fuc?1-2Gal?1-3GlcNAc” or “Fuc?1-2Gal?1-3GalNAc” and capable of sensitively determining the undifferentiated state of stem cells using a culture supernatant of stem cells. Also found is BC2LCN lectin or a modified product thereof capable of sensitively recognizing the “undifferentiation sugar chain marker” as excellent “probe for detecting the undifferentiation sugar chain marker” capable of determining the undifferentiation status of cells using a culture supernatant.Type: GrantFiled: October 31, 2012Date of Patent: November 22, 2016Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Hiroaki Tateno, Jun Hirabayashi, Yuzuru Ito, Yasuko Onuma, Makoto Asashima, Atsushi Kuno, Masaki Warashina, Masakazu Fukuda
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Patent number: 9458513Abstract: The present invention relates to an oligonucleotide which is designed on the basis of a nucleotide sequence shown in SEQ ID NO: 1 or SEQ ID NO: 2 and hybridizes with the endogenous plasmid gene of Chlamydia trachomatis, oligonucleotide primer and probe for detecting Chlamydia trachomatis, the detection method of Chlamydia trachomatis using said primer and probe, and a primer for detecting Chlamydia trachomatis of said oligonucleotide or the use to a probe design.Type: GrantFiled: March 17, 2011Date of Patent: October 4, 2016Assignee: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Tomokazu Ishikawa, Hiromi Kumon
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Publication number: 20160272924Abstract: The present invention relates to a cleaning agent for a semiconductor substrate having a copper wiring film or a copper alloy wiring film, and a cobalt-containing film to be used in a post-process of a chemical mechanical polishing process, comprising (A) an organic acid represented by general formula described in the present specification, (B) amines selected from the group consisting of (B-1) diamines, (B-2) amidines, (B-3) azoles, and (B-4) pyrazines or pyrimidines, represented by general formulae described in the present specification, (C) a hydroxylamine derivative, and (D) an oxygen scavenger represented by general formula described in the present specification, and being an aqueous solution having a pH of 10 or higher; and a processing method for the surface of a semiconductor substrate, having a copper wiring film or a copper alloy wiring film, and a cobalt-containing film, which comprises using the cleaning agent.Type: ApplicationFiled: November 7, 2014Publication date: September 22, 2016Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Takayuki Kajikawa, Kohei Hayashi, Hironori Mizuta, Tsutomu Watahiki
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Patent number: 9448244Abstract: The present invention addresses the problem of providing a chelate color former which can measure the concentration of iron with high sensitivity and with low blank values when measuring the concentration of iron, and an iron concentration measurement method and kit that use this chelate color former. The present invention relates to: a compound represented by following formula [1] or a salt thereof wherein, R1 and R2 each independently represent —SO3H or —CO2H; an iron concentration measurement method in which the compound is used as a chelate color former, the compound is brought into contact with iron in a sample, and the concentration of iron in the sample is measured on the basis of the degree of resulting color development; and a kit to be used therein.Type: GrantFiled: October 15, 2013Date of Patent: September 20, 2016Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Yoshikazu Fujita, Toshinari Ohashi, Naoyuki Yamamoto, Takashi Takagaki, Satoshi Hasaba
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Patent number: 9429572Abstract: An object of the present invention is to provide a method for forming a complex between an analyte or an analog thereof, and a substance formable the complex with said analyte or said analog thereof (the complex forming substance), in a short time and in high reaction efficiency, and a method for separating a complex formed, and a complex forming substance not involved in formation of said complex or an analog not involved in formation of said complex rapidly, simply and in high accuracy, along with a method for measuring an analyte in a sample in high sensitivity.Type: GrantFiled: August 24, 2006Date of Patent: August 30, 2016Assignee: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Tomohisa Kawabata, Shinji Satomura, Henry Garrett Wada
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Publication number: 20160177457Abstract: The object of the present invention is to provide: an etching agent for a titanium-based metal on a semiconductor substrate, which suppresses decomposition of hydrogen peroxide, has a long liquid service life, and has less need for controlling the concentration of hydrogen peroxide in the etching agent, even in the cases where the etching agent is used for a semiconductor substrate having the titanium-based metal and a metallic copper or a metal alloy; an etching method; and an etching agent preparation liquid for use by mixing with hydrogen peroxide.Type: ApplicationFiled: July 3, 2014Publication date: June 23, 2016Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Takahiro YOKOMIZO, Hiroyuki TSURUMOTO, Masahiko KAKIZAWA
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Patent number: 9279809Abstract: Provided are a method for accurately evaluating the differentiation status of stem cells by selectively staining only stem cells in an undifferentiated state, and a method for positively isolating only stem cells in an undifferentiated state. Specifically provided is a method for determining differentiation of a cell comprising a step of contacting a test cell with a probe comprising protein (A) or (B) below and a step of detecting the presence of binding of the probe to the test cell. The method for determining differentiation of a cell is capable of detecting the presence or absence of an undifferentiated stem cell in test cells by using a probe that specifically reacts with undifferentiated stem cells and detecting the presence of bonding to the test cell.Type: GrantFiled: February 27, 2013Date of Patent: March 8, 2016Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Hiroaki Tateno, Jun Hirabayashi, Makoto Asashima, Yuzuru Ito, Yasuko Onuma, Masaki Warashina, Masakazu Fukuda
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Publication number: 20160060584Abstract: It is a subject of the present invention to provide a cleaning agent for a substrate having a metal wiring, and a cleaning method for a semiconductor substrate comprising that the cleaning agent is used, by which following effects (1) to (5) are obtained, in a cleaning process after chemical mechanical polishing (CMP) in a manufacturing process of a semiconductor device. (1) Residues of fine particles (polishing agents) used in the CMP process, fine particles (metal particles) derived from a polished metal, an anticorrosive, and the like, can be removed sufficiently. (2) A coating film (protective film: oxidation resistant film) on a surface of the metal wiring, containing a complex between an anticorrosive, such as benzotriazole or quinaldic acid, and a surface metal of the metal wiring, formed in the CMP process, can be removed (stripped) sufficiently. (3) An oxide film containing a metal oxide can be formed after removal (stripping) of the coating film.Type: ApplicationFiled: April 9, 2014Publication date: March 3, 2016Applicant: Wako Pure Chemical Industries, Ltd.Inventors: Hironori Mizuta, Tsutomu Watahiki, Tsuneaki Maesawa
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Patent number: 9263767Abstract: It is an object of the present invention to provide an electrochemical device having an electrolytic solution having high current density and high oxidation resistance, as well as high safety, where dissolution and deposition of magnesium progress repeatedly and stably. The present invention relates to the electrolytic solution for an electrochemical device comprising (1) the supporting electrolyte composed of a magnesium salt and (2) at least one or more kinds of the compound represented by the following general formula [2], as well as the electrochemical device comprising said electrolytic solution, a positive electrode, a negative electrode and a separator.Type: GrantFiled: July 26, 2012Date of Patent: February 16, 2016Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Tsutomu Watahiki, Takahiro Kiyosu, Kuniaki Okamoto
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Publication number: 20160040013Abstract: The present invention is to provide a colored composition having higher heat resistance compared with conventional colored compositions. The present invention further relates to: “a polymer having a monomer unit derived from a monomer which has (i) a cationic rhodamine derivative having, as an counter anion, an anion including an aryl group having an electron-withdrawing substituent and an anion group and (ii) an ethylenically unsaturated bond”, “a monomer which has (i) a cationic rhodamine derivative having, as an counter anion, an anion including an aryl group having an electron-withdrawing substituent and an anion group and (ii) an ethylenically unsaturated bond”, “a colored composition comprising the above-described polymer or the monomer”, and “a colored composition for a color filter comprising the above-described polymer or the monomer”.Type: ApplicationFiled: February 13, 2014Publication date: February 11, 2016Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Yukihiko Shida, Taeyeon Kim, Tomotaka Totsuka, Masahiro Takano
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Patent number: 9255070Abstract: The subject of the present invention is to provide a method for deuteration, which can obtain a compound having an aromatic ring and/or a heterocyclic ring at an improved deuteration ratio. The present invention relates to a method for deuteration of a compound having an aromatic ring and/or a heterocyclic ring, comprising reacting the compound having an aromatic ring and/or a heterocyclic ring with a heavy hydrogen source in the presence of an activated mixed catalyst of not less than two kinds of catalysts selected from among a palladium catalyst, a platinum catalyst, a rhodium catalyst, an iridium catalyst, a ruthenium catalyst, a nickel catalyst and a cobalt catalyst.Type: GrantFiled: December 21, 2004Date of Patent: February 9, 2016Assignee: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Nobuhiro Ito, Tsuneaki Maesawa, Kazushige Muto, Kosaku Hirota, Hironao Sajiki
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Patent number: 9257720Abstract: The present invention provides a non-aqueous electrolytic solution including a methylenebissulfonate derivative and improving initial irreversible capacity and other characteristics of a battery such as a cycle characteristics, electric capacity, and storage characteristics; a method for producing thereof; and a battery using the electrolytic solution. The non-aqueous electrolytic solution includes: (1) a non-aqueous solvent comprising at least one selected from a cyclic carbonate ester, a straight chained carbonate ester and/or a cyclic carboxylic acid ester, (2) a lithium salt which may be dissolved in the non-aqueous solvent, as an electrolyte salt, and (3) a methylenebissulfonate derivative of formula [1]: The method includes steps of dissolving a lithium salt in a non-aqueous solvent, and then dissolving the methylenebissulfonate derivative.Type: GrantFiled: August 2, 2011Date of Patent: February 9, 2016Assignee: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Kuniaki Okamoto, Motoshige Sumino, Tsutomu Watahiki, Kouki Ohkubo, Tatsuko Ikeda