Patents Assigned to Washington University & Chiron Corp.
  • Method for using lipoprotein associated coagulation inhibitor to treat sepsis
    Patent number: 6063764
    Abstract: A method for prophylactically or therapeutically treating sepsis or septic shock is described, wherein an inhibitor to tissue factor is administered to septic patients. Additionally, a method for treating inflammation is described wherein the inhibitor is administered to pateints. This inhibitor is termed lipoprotein associated coagulation inhibitor, or commonly LACI. It is 38 kD and has 276 amino acids. LACI has now been shown to be useful for the treatment of sepsis, septic shock and inflammation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 16, 2000
    Assignee: Washington University & Chiron Corp.
    Inventors: Abla A. Creasey, George J. Broze