Abstract: Method steps for correcting vision in an eye that uses a customized phakic IOL composing: (1) measuring one or more wavefront aberrations of the eye: (2) designing a wavefront-customized correction profile for an Intraocular Lens (IOL); (3) creating a customized IOL with the customized correction profile; and (4) implanting the customized IOL in the eye. Alternatively, an uncorrected IOL is first implanted and aligned in the eye, followed by in-situ scanning a femtosecond laser spot across the implanted IOL to locally change the Index of Refraction of the IOL material and create an in-situ customized IOL.

Abstract: This invention comprises a combined optical wavefront aberrometer and topographer system that is used in conjunction with a contact lens that has a plurality of fiducial marks disposed on the lens. The fiducial marks are located radially inside of the undilated pupil's diameter. The optical imaging capacity of the aberrometer is used to measure and monitor any misalignments of the contact lens's position (XY decentration) and/or rotation. Image analysis algorithms are used to track the positions of the fiducial marks, and, hence, the amount of geometric misalignment of the contact lens can be calculated. The fiducial marks can comprise micro ink spots, or depressions in the surface of the contact lens (e.g., divots, dimples, pits), or other small surface features, including raised bumps, which can help to stabilize motions of the contact lens on the eye.

Abstract: This disclosure teaches an eye-tracking optical instrument and methodology for dynamically tracking Purkinje reflection spots on a patient's eye in real-time, which allows the XYZ position and tip/tilt of ocular structures on or inside of the eye to be measured in real-time with high precision. When used in combination with programmable groups of infrared LED light sources, unique patterns of Purkinje reflections from the cornea and/or internal ocular surfaces within the eye may be accurately identified. An Optical Coherence Tomography (OCT) optical system and/or an off-axis Range Finding Camera may be combined with the eye-tracking optical system to provide Z-axis distance information.

Abstract: A system for correcting vision in an eye that uses a premium, customized IOL, the system comprising: (1) optical aberrometer means for measuring wavefront aberrations of the eye; (2) computer means for designing a wavefront-customized correction profile for the IOL; (3) manufacturing means for creating a customized IOL with the wavefront-corrected profile; and (4) surgical means for implanting the customized IOL in the eye. Alternatively an uncorrected IOL is first implanted and aligned in the eye, followed by in-situ scanning a femtosecond laser spot across the implanted IOL to locally change an index of Refraction of the IOL material in-situ.

Abstract: This invention, a Purkinjenator™ optical system, is an eye-tracker and methodology for tracking Purkinje reflection images from a human eye in real-time, which allows for the XYZ position and tip/tilt of structures inside the eye to be determined in real-time. When used in combination with programmable groups of IR LED light sources, unique patterns of Purkinje reflections from internal surfaces (and corneal surfaces) can be identified. Thus, XYZ positioning and tip/tilt of internal structures can be accurately and rapidly determined. An Optical Coherence Tomography (OCT) optical system can be combined with the Purkinjenator™ optical system to provide Z-axis distance information.

Abstract: This invention relates to optical methods and optical systems for making both on-axis and wide-field, peripheral off-axis wavefront measurements of an eye; and for designing and manufacturing wavefront-guided customized contact lens useful for myopia control. The wide-field optical instrument can comprise either (1) a multi-axis optical configuration using multiple off-axis beamlets, or (2) an instrument comprising a rotatable scanning mirror that generates off-axis probe beams.

Abstract: This disclosure relates to methods and devices for designing customized contact lenses, by initially making dynamic wavefront sensor measurements through a trial contact lens that is fitted on an eye, and then calculating a WaveFront Guided (WFG) correction to be applied to the trial contact lens that reduces the RMS level of aberrations as much as practically possible. The output of the wavefront correction program is a customized lathe file that the manufacturer can use to make customized contact lenses on a lathe. The method works best for soft contact lenses and scleral lenses.

Abstract: A method and system for correcting vision in an eye that uses a wavefront-customized phakic or pseudophakic Intraocular Lens (IOL), the method comprising: (1) measuring wavefront aberrations of the eye; (2) designing a wavefront-customized correction profile for an IOL; (3) creating a customized IOL with the customized correction profile; and (4) implanting the customized IOL in the eye, without having to remove the natural lens. Alternatively, an uncorrected IOL is implanted first, followed by scanning a femtosecond laser spot across the implanted IOL to locally change the Index of Refraction of the IOL material and create an in-situ customized IOL.

Abstract: This invention relates to methods and devices for designing customized contact lenses, by initially making dynamic wavefront sensor measurements through a trial contact lens that is fitted on an eye, and then calculating a WaveFront Guided (WFG) correction to be applied to the trial contact lens that reduces the RMS level of aberrations as much as practically possible. The output of the wavefront correction program is a customized lathe file that the manufacturer can use to make customized contact lenses on a lathe. The method works best for soft contact lenses and scleral lenses.

Abstract: A method for correcting aberrations of a patient's eye with a customized contact lens, including determining an optimal XY location and an optimal angular orientation, a, for placing correction optics on the customized contact lens by using an optical instrument to measure XY offsets (?X, ?Y) and X, Y, Z tilt angles, (?x, ?y, ?), respectively, of a predicate contact lens while disposed on the patient's eye is disclosed. The predicate contact lens and the customized contact lens can be a scleral contact lens or a normal contact lens. The optical instrument can comprise a wavefront aberrometer and/or a corneal topographer. The correction optics include a wavefront-customized contact lens with a built-in, optimized wavefront-guided correction patch. The predicate contact lens can include three or more fiducial marks inside of the pupil, which can be used to determine the XY center of the predicate contact lens when placed on the patient's eye.

Abstract: Systems and methods for manufacturing a wavefront-customized contact lens. The systems include: (1) an optical instrument for measuring ocular imperfections of a patient's eye; (2) a computer for designing a mold and pin design used for manufacturing a wavefront-customized contact lens that corrects the ocular imperfections; (3) a fabrication machine for fabricating a wavefront-customized mold that includes corrections for the ocular imperfections; and (4) a manufacturing equipment for manufacturing a wavefront-customized contact lenses that uses the wavefront-customized mold; wherein the wavefront-customized mold design and wavefront-guided contact lens manufacturing are uniquely customized for each patient's eye. The optical means can be a wavefront aberrometer with, or without, a profilometer and/or an Optical Coherence Tomography (OCT) module. The wavefront-customized contact lens can be a soft contact lens or a rigid, gas permeable contact lens.