Patents Assigned to Webb-Waring Institute for Biomedical Research
  • Genetically modified manganese superoxide dismutase for treating oxidative damage
    Patent number: 6190658
    Abstract: This invention discloses a genetically modified manganese superoxide dismutase nucleic acid molecule and protein. Also disclosed are recombinant molecules, recombinant cells, therapeutic compositions and methods of using the modified manganese superoxide dismutase to treat oxidative damage.
    Type: Grant
    Filed: May 8, 1998
    Date of Patent: February 20, 2001
    Assignee: Webb-Waring Institute for Biomedical Research
    Inventors: Joe M. McCord, Bifeng Gao, Sonia C. Flores
  • Method of using LDH as a predictor of the adult respiratory distress syndrome in septic patients
    Patent number: 5639629
    Abstract: At the initial diagnosis of sepsis (6-24 h before the development of ARDS), serum lactate dehydrogenase (LDH) activity level is increased in septic patients who subsequently develop ARDS compared to healthy patients and septic patients who do not develop ARDS. A method is disclosed for predicting the occurrence of ARDS in a septic patient from the patient's serum level of LDH activity, which method facilitates identification of subsets of patients destined to develop ARDS and allows prospective treatment of such septic patients.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: June 17, 1997
    Assignees: The Regents of the University of Colorado, The Webb-Waring Institute for Biomedical Research
    Inventors: John E. Repine, Jonathan A. Leff