Patents Assigned to Well Stone Co.
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Patent number: 11896625Abstract: Provided are: a method of producing a therapeutic agent for skin lesions suitable for treatment or prevention of a skin lesion such as a bedsore; and a therapeutic agent for skin lesions produced by the production method. The method of producing a therapeutic agent for skin lesions characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the therapeutic agent for skin lesions produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: September 21, 2021Date of Patent: February 13, 2024Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Makino
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Patent number: 11642380Abstract: Provided are: a method for producing a nasal drop composition suitable for treatment or prevention of a disease or symptom in the nasal cavities; and a nasal drop composition produced by the production method. The nasal drop composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the nasal drop composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: June 29, 2021Date of Patent: May 9, 2023Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Makino
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Patent number: 11266595Abstract: Provided are: a method for producing a deodorant which is derived from earthworm castings and can be used in a liquid form; and a deodorant. The deodorant production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the deodorant produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: December 16, 2016Date of Patent: March 8, 2022Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Ishii
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Patent number: 11260022Abstract: Provided are: a method for producing an oral composition suitable for treatment or prevention of a disease or symptom in the oral cavity; and an oral composition produced by the production method. The oral composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the oral composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: March 16, 2018Date of Patent: March 1, 2022Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Makino
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Publication number: 20220000937Abstract: Provided are: a method of producing a therapeutic agent for skin lesions suitable for treatment or prevention of a skin lesion such as a bedsore; and a therapeutic agent for skin lesions produced by the production method. The method of producing a therapeutic agent for skin lesions characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the therapeutic agent for skin lesions produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: ApplicationFiled: September 21, 2021Publication date: January 6, 2022Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka MAKINO
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Publication number: 20210322487Abstract: Provided are: a method for producing a nasal drop composition suitable for treatment or prevention of a disease or symptom in the nasal cavities; and a nasal drop composition produced by the production method. The nasal drop composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the nasal drop composition produced by the production method.Type: ApplicationFiled: June 29, 2021Publication date: October 21, 2021Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka MAKINO
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Patent number: 11147842Abstract: Provided are: a method of producing a therapeutic agent for skin lesions suitable for treatment or prevention of a skin lesion such as a bedsore; and a therapeutic agent for skin lesions produced by the production method. The method of producing a therapeutic agent for skin lesions characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the therapeutic agent for skin lesions produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: March 16, 2018Date of Patent: October 19, 2021Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Makino
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Patent number: 11077152Abstract: Provided are: a method for producing a nasal drop composition suitable for treatment or prevention of a disease or symptom in the nasal cavities; and a nasal drop composition produced by the production method. The nasal drop composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the nasal drop composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: GrantFiled: March 16, 2018Date of Patent: August 3, 2021Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takeshi Okamoto, Sayaka Makino
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Publication number: 20200093868Abstract: Provided are: a method of producing a therapeutic agent for skin lesions suitable for treatment or prevention of a skin lesion such as a bedsore; and a therapeutic agent for skin lesions produced by the production method. The method of producing a therapeutic agent for skin lesions characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the therapeutic agent for skin lesions produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: ApplicationFiled: March 16, 2018Publication date: March 26, 2020Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka MAKINO
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Patent number: 10576108Abstract: An object of the present invention is to provide: a Tau protein production accelerator containing a natural product as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. Provided are: a Tau protein production accelerator containing a dry powder ground product and/or extract of an earthworm as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. The disease caused by Tau protein deficiency is preferably Alzheimer's disease.Type: GrantFiled: July 17, 2019Date of Patent: March 3, 2020Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takayuki Nemoto, Takeshi Okamoto
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Publication number: 20190365825Abstract: Provided are: a method for producing a nasal drop composition suitable for treatment or prevention of a disease or symptom in the nasal cavities; and a nasal drop composition produced by the production method. The nasal drop composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the nasal drop composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: ApplicationFiled: March 16, 2018Publication date: December 5, 2019Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka MAKINO
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Publication number: 20190365639Abstract: Provided are: a method for producing an oral composition suitable for treatment or prevention of a disease or symptom in the oral cavity; and an oral composition produced by the production method. The oral composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the oral composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: ApplicationFiled: March 16, 2018Publication date: December 5, 2019Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka MAKINO
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Publication number: 20190365826Abstract: An object of the present invention is to provide: a Tau protein production accelerator containing a natural product as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. Provided are: a Tau protein production accelerator containing a dry powder ground product and/or extract of an earthworm as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. The disease caused by Tau protein deficiency is preferably Alzheimer's disease.Type: ApplicationFiled: July 17, 2019Publication date: December 5, 2019Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takayuki NEMOTO, Takeshi OKAMOTO
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Patent number: 10398740Abstract: An object of the present invention is to provide: a Tau protein production accelerator containing a natural product as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. Provided are: a Tau protein production accelerator containing a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. The disease caused by Tau protein deficiency is preferably Alzheimer's disease.Type: GrantFiled: November 2, 2015Date of Patent: September 3, 2019Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takayuki Nemoto, Takeshi Okamoto
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Publication number: 20190060215Abstract: Provided are: a method for producing a deodorant which is derived from earthworm castings and can be used in a liquid form; and a deodorant. The deodorant production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the deodorant produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.Type: ApplicationFiled: December 16, 2016Publication date: February 28, 2019Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka ISHII
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Patent number: 10155012Abstract: An object of the present invention is to provide: a catecholamine production accelerator comprising a natural product as an active ingredient; a therapeutic agent and preventive agent for diseases caused by catecholamine deficiency; and food compositions for the treatment or prevention of diseases caused by catecholamine deficiency. Provided are: a catecholamine production accelerator comprising a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic agent and preventive agent for a disease caused by catecholamine deficiency; and loud compositions for the treatment or prevention of a disease caused by catecholamine deficiency. It is preferred that the disease caused by catecholamine deficiency be selected from the group consisting of Alzheimer's disease and Parkinson's disease.Type: GrantFiled: January 13, 2015Date of Patent: December 18, 2018Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takayuki Nemoto, Takeshi Okamoto
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Patent number: 10105402Abstract: An object of the present invention is to provide: a catecholamine production accelerator comprising a natural product as an active ingredient; a therapeutic agent and preventive agent for diseases caused by catecholamine deficiency; and food compositions for the treatment or prevention of diseases caused by catecholamine deficiency. Provided are: a catecholamine production accelerator comprising a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic agent and preventive agent for a disease caused by catecholamine deficiency; and loud compositions for the treatment or prevention of a disease caused by catecholamine deficiency. It is preferred that the disease caused by catecholamine deficiency be selected from the group consisting of Alzheimer's disease and Parkinson's disease.Type: GrantFiled: January 13, 2015Date of Patent: October 23, 2018Assignee: WELL STONE CO.Inventors: Yoichi Ishii, Takayuki Nemoto, Takeshi Okamoto
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Publication number: 20180147243Abstract: An object of the present invention is to provide: an amyloid ? fibril decomposing agent containing a natural product as an active ingredient; a therapeutic or preventive agent for a disease caused by amyloid ? fibril formation; and a therapeutic or preventive food composition for a disease caused by amyloid ? fibril formation. Provided are: an amyloid ? fibril decomposing agent containing a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic or preventive agent for a disease caused by amyloid ? fibril formation; and a therapeutic or preventive food composition for a disease caused by amyloid ? fibril formation. The disease caused by amyloid ? fibril formation is preferably Alzheimer's disease.Type: ApplicationFiled: July 14, 2016Publication date: May 31, 2018Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takeshi OKAMOTO, Sayaka ISHII
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Publication number: 20170348357Abstract: An object of the present invention is to provide: a Tau protein production accelerator containing a natural product as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. Provided are: a Tau protein production accelerator containing a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic or preventive agent for a disease caused by Tau protein deficiency; and a therapeutic or preventive food composition for a disease caused by Tau protein deficiency. The disease caused by Tau protein deficiency is preferably Alzheimer's disease.Type: ApplicationFiled: November 2, 2015Publication date: December 7, 2017Applicant: WELL STONE CO.Inventors: Yoichi ISHII, Takayuki NEMOTO, Takeshi OKAMOTO
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Patent number: 9511098Abstract: A method for producing dry earthworm powder, by which dry earthworm powder having high-titer enzymes can be produced while removing toxic substances contained in the bodies of earthworms, is provided. The method comprises: contacting a live earthworm with a chloride(s) of at least one metal selected from the group consisting of potassium, sodium, magnesium and calcium; and subsequently contacting the live earthworm with powder of a hydroxycarboxylic acid(s) and diluting the resulting mixture with water to adjust pH to 2 to 5, followed by leaving the live earthworm to stand for 3 to 180 minutes, washing the live earthworm with water, grinding the washed live earthworm and freeze-drying the obtained ground product.Type: GrantFiled: October 5, 2011Date of Patent: December 6, 2016Assignee: WELL STONE CO.Inventor: Kazuyuki Ishii