Abstract: A computer-implemented method for improving compliance with a therapeutic regimen for each of a plurality of patients includes, for each patient, causing presentation by the server to the patient via an application running on the mobile computing device, on at least a daily basis, of (i) an updated list of items to be performed by the patient on the date of presentation on the updated list and (ii) a region on a display of the mobile computing device for reporting performance of items on the updated list so as to cause sending by the mobile computing device to the server of patient compliance data; and receiving at the server from the mobile computing device the patient compliance data, storing such data and using such data in calculating the updated list for presentation to the patient via the mobile computing device on a subsequent occasion.