Abstract: Orthopedic support devices are provided that include a main body having at least one border area and causing targeted compression to a body part over which an orthopedic support device is worn and that further include at least one transition cuff located at a border area of the main body, wherein the main body is made of a material that has a predetermined elastic modulus and wherein the at least one transition cuff is made of a material that has a lower predetermined elastic modulus than the material from which the main body is made such that the presence of the at least one transition cuff is effective to reduce displacement of soft tissue at the border area that is caused by the targeted compression of the main body.

Abstract: Orthopedic support devices are provided that include a first layer of elastomeric material is attached directly atop or around a layer of a spacer material, wherein the first layer provides support and/or compression, and the second layer provides breathability and wicking and wherein characteristics of the first layer can be varied in order to vary the location, amount and/or level of compression provided by the support device.