Abstract: The present invention relates to novel derivatives of glycyrrhetinic acid, compositions comprising said derivatives and their use in the treatment of conditions or diseases that benefits from an upregulation of PPAR? and/or a downregulation of the expression or activity of one or more specificity (Sp) proteins, such as cancer, diabetes and Huntington's disease.
Type:
Application
Filed:
February 5, 2013
Publication date:
August 15, 2013
Applicants:
The Texas A&M University System, Wellington Laboratories Inc.
Inventors:
Stephen H. Safe, Sudhakar Chintharlapalli, Alan McAlees, Robert McCrindle
Abstract: The present invention relates to novel derivatives of glycyrrhetinic acid, compositions comprising said derivatives and their use in the treatment of conditions or diseases that benefit from an upregulation of PPAR&ggr; and/or a downregulation of the expression or activity of one or more specificity (Sp) proteins, such as cancer, diabetes and Huntington's disease.
Type:
Grant
Filed:
June 27, 2007
Date of Patent:
March 5, 2013
Assignees:
Wellington Laboratories Inc., The Texas A&M University System
Inventors:
Stephen H. Safe, Sudhakar Chintharlapalli, Alan McAlees, Robert McCrindle