Abstract: A method of detecting the likelihood of a seizure event in a patient includes at successive expirations of a first time interval, determining a first likelihood that the patient is experiencing a seizure based on electrodermal activity and a movement of a limb of the patient. The method also includes at successive expirations of a second time interval, determining whether the patient experienced a seizure in a second time period preceding the determining based on a heart rate of the patient. In response to determining that the third comparison result satisfies at least a third detection criterion, the method compares electrodermal activity and the movement of a limb of the patient to determine a second likelihood. In response to determining that the second likelihood satisfies a second detection criterion, the method triggers presentation of a second alert regarding a potential seizure.