Abstract: A cardan joint steering titanium alloy hand and foot cooperatively operated bicycle capable of being ridden with one leg comprises a bicycle front wheel, a front wheel fork frame, a bicycle rear wheel, a frame body, a seat cushion assembly, a steering handlebar, paired chain wheels and a rear wheel fork frame. The upper end of a front fork rotating shaft and the lower end of an assisting stem are connected through a cardan joint component, symmetric ratchet wheels are provided on the two sides of the bicycle rear wheel, the paired chain wheels are fixed to the two sides of a frame middle shaft, pedal shaft pins are symmetrically provided on the outer sides of the paired chain wheels, and the paired chain wheels and the symmetric ratchet wheels are connected through symmetric chains.