Patents Assigned to Western Health Care Network
  • Viral variants and methods for detecting same
    Publication number: 20030124096
    Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
    Type: Application
    Filed: October 1, 2002
    Publication date: July 3, 2003
    Applicant: Western Health Care Network
    Inventors: Stephen A. Locarnini, Angeline I. Bartholomeusz, Thein T. Aye, Robert A. de Man
  • Viral variants and methods for detecting same
    Patent number: 6555311
    Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: April 29, 2003
    Assignee: Western Health Care Network
    Inventors: Stephen A Locarnini, Angeline I. Bartholomeusz, Thein T. Aye, Robert A. de Man