Abstract: Curved origami-based meta-material, manufacturing method of the same, curved origami-based haptic module and a method for producing active mechanical haptics. The curved origami-based metamaterial includes a panel having a single curved crease extending in its longitudinal direction, which divides the panel into two facets at its two opposite sides. The panel is configured to be folded along the single curved crease to form a folding angle between the two facets. The folding angle is configured to be adjustable to achieve a variable stiffness when loaded in a vertical direction of the folded panel, covering positive stiffness to negative stiffness.

Abstract: A wing structure for a vehicle includes a plurality of multi-connecting-rod structures, the multi-connecting-rod structures are arranged along the main body of the vehicle, each of the multi-connecting-rod structure being arranged in a direction extending from a main body of the vehicle to a wingtip, each of the multi-connecting-rod structures comprising a plurality of connecting rods, and the connecting rods that are adjacent to each other being connected by a motor, a plurality of groups of ribs are sleeved onto each of the multi-connecting-rod structures, and each group of the ribs comprises a plurality of rib units, wherein in the same group of the ribs, adjacent rib units are connected by a ball hinge. The present technical solution can perform adjustment on a complex flow field or environment, the motion speed and the motion efficiency are significantly improved, and high maneuvering actions can be achieved.

Abstract: A fast harmless treatment device for a hazardous flexible material is provided. The fast harmless treatment device includes a container body and a container lid, where a bottom plate is fixed at a near-bottom position of the container body; a movable plate is provided in the container body; there is a gap between an outer edge of the movable plate and an inner wall of the container body; a movement mechanism is configured to compress a hazardous flexible material on the movable plate towards the container lid; the container lid and the movable plate each are provided therein with a heating tube; and a heating tube and a blowing device are provided on the bottom plate to cause high-temperature convection and disinfect an aerosol-mixed gas.

Abstract: 1, 2, 4, 5-tetraoxane compounds and derivatives thereof that have anticancer properties are disclosed. Pharmaceutical compositions and pharmaceutical formulations in unit dosage form suitable for the delivery of the compounds to a subject in need thereof are disclosed. The pharmaceutical compositions or formulations may include one or more active agents in addition to the compounds, such as one or more additional anticancer agents. Methods for treating a cancer, reducing a cancer, or treating or ameliorating one or more symptoms associated with a cancer in a subject are also disclosed. The methods include (i) administering to a subject in need thereof an effective amount of the compound (s). The compound (s) can be administered by oral administration, parenteral administration, inhalation, mucosal administration, or a combination thereof. The compound can selectively kill cancer cells and/or cancer stem cells over non-cancerous cells by triggering ferroptosis in the cancer cells and/or cancer stem cells.

Abstract: A lattice light sheet microscope includes a single spatial light modulator (SLM), the optical modulation plane of which conjugates to an image plane of an excitation objective and which is configured to: generate an optical lattice by loading a phase map obtained from a central cross section of a corresponding optical lattice of a desired lattice light sheet, and tile the optical lattice by loading a phase map obtained from an off-center cross section of the corresponding optical lattice. The lattice light sheet microscope also includes a transparent annular diaphragm arranged at a plane conjugating to the entrance pupil of the excitation objective lens. The lattice light sheet microscope further includes a first galvanometer configured to: scan each optical lattice in the extending direction thereof so as to form a tiled lattice light sheet.

Abstract: The disclosed invention is generally in the field of synthetic small molecules and their use as drug, in particular in the treatment of cancer. Also provided is a method of inhibiting cancer stem cells. Also provided is a method for treatment of cancers and other diseases by affecting mitochondrial functions. Also provided is a method of making and using of the compounds.

Abstract: The disclosure provides at compounds of Formula I, compositions comprising the same, and methods of using the same, including use in treating a disease and/or a symptom of a disease caused by a coronavirus.