Patents Assigned to Wex Pharmaceuticals Inc.
  • TETRODOTOXIN LIQUID FORMULATIONS
    Publication number: 20240226105
    Abstract: A stable formulation comprising tetrodotoxin, and/or a derivative, analog, or a pharmaceutically acceptable salt thereof, wherein the formulation comprises the tetrodotoxin component and one or more solvents, pH adjusting agents, buffering agents, and stabilizing agents.
    Type: Application
    Filed: April 22, 2022
    Publication date: July 11, 2024
    Applicant: Wex Pharmaceuticals Inc.
    Inventors: Meng ZHOU, Donald C. K. WONG
  • Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy
    Patent number: 10149852
    Abstract: The present disclosure describes the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogs/derivatives as well as their acceptable salts, for treating neuropathic pain resulting from chemotherapy. Methods, compositions, dose units and dose forms of tetrodotoxin related to the use are described.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 11, 2018
    Assignee: WEX PHARMACEUTICALS INC.
    Inventors: Helmut Heinrich Buschmann, Jose Miguel Vela Hernandez, Jose Manuel Baeyens, Susan Lu, Donald Wong, Walter Korz
  • USE OF SODIUM CHANNEL BLOCKERS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY
    Publication number: 20100215771
    Abstract: The present invention refers to the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for the production of a medicament for the treatment of neuropathic pain resulting from chemotherapy.
    Type: Application
    Filed: March 26, 2007
    Publication date: August 26, 2010
    Applicant: WEX PHARMACEUTICALS INC.
    Inventors: Helmut Heinrich Buschmann, Jose Miguel Vela Hernandez, Jose Manuel Baeyens
  • Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment
    Publication number: 20100144767
    Abstract: The invention provides methods for treating visceral pain and pain associated with therapy. The compounds useful in the methods of the invention are blockers of sodium ion channels, and in particular compounds that bind to the SS1 or SS2 extracellular mouth of the ?-subunit thereof. Particularly useful compounds are saxitoxin and its derivatives and analogues and tetrodotoxin and its derivatives and analogues.
    Type: Application
    Filed: August 25, 2006
    Publication date: June 10, 2010
    Applicant: WEX PHARMACEUTICALS, INC.
    Inventors: Kim Noel Fisher, Anh Ho Ngoc, Edge Renfeng Wang
  • Use of sodium channel blockers for the management of musculoskeletal pain
    Publication number: 20100048592
    Abstract: The invention provides methods for managing musculoskeletal pain. The compounds useful in the methods of the invention are blockers of sodium ion channels, and in particular compounds that bind to the SS1 or SS2 extracellular mouth of the a-subunit thereof. Particularly useful compounds are saxitoxin and its derivatives and analogues and tetrodotoxin and its derivatives and analogues.
    Type: Application
    Filed: August 25, 2006
    Publication date: February 25, 2010
    Applicant: Wex Pharmaceuticals Inc.
    Inventors: Kim Noel Fisher, Anh Ho Ngoc, Edge Renfeng Wang
  • Tetrodotoxin And Its Derivatives For The Treatment Of Central-Nervously Derived Neuropathic Pain
    Publication number: 20090143415
    Abstract: The present invention refers to the use of a sodium channel blocker such as tetrodotoxin or saxitoxin, their analogues and derivatives as well as their physiologically acceptable salts, in medicinal products for human therapeutics for the treatment of central-nervously derived neuropathic pain.
    Type: Application
    Filed: September 21, 2005
    Publication date: June 4, 2009
    Applicant: Wex Pharmaceuticals, Inc.
    Inventors: Helmut Heinrich Buschmann, Frank Hay Kong Shum, Kim Noel Fisher, Anh Ho Ngoc, Michel Hamon