Abstract: Packaging cell lines useful for the generation of helper-free recombinant retroviruses with amphotropic or ecotropic host ranges, methods of constructing such packaging cell lines and methods of using the recombinant retroviruses to introduce DNA of interest into eukaryotic cells, both in vitro and in vivo.
Type:
Grant
Filed:
February 22, 1994
Date of Patent:
September 12, 1995
Assignee:
Whitehead Institue For Biomedical Research