Patents Assigned to Whittemore Peterson Institute for Neuro-Immune Disease
  • STRAINS OF XENOTROPIC MURINE LEUKEMIA-RELATED VIRUS AND METHODS FOR DETECTION THEREOF
    Publication number: 20110311484
    Abstract: Provided are novel strains of Xenotropic Murine Leukemia Virus-Related Virus (XMRV), or polynucleotides or polypeptides thereof. Identified herein are nucleic acid changes or amino acid changes identified in XMRV strains isolated from subjects. Also provided are methods of detecting such XMRV strains based at least in part on the identified nucleic acid changes or amino acid changes.
    Type: Application
    Filed: April 6, 2011
    Publication date: December 22, 2011
    Applicant: Whittemore Peterson Institute for Neuro-Immune Disease
    Inventors: Judy A. Mikovits, Vincent C. Lombardi
  • DETECTION OF XENOTROPIC MURINE LEUKEMIA VIRUS
    Publication number: 20110151431
    Abstract: Methods of detecting, diagnosing, monitoring or managing an XMRV-related neuroimmune disease such as chronic fatigue syndrome or XMRV-related lymphoma such as mantle cell lymphoma in a subject are disclosed. These methods comprise determining presence, absence or quantity an XMRV nucleic acid in a sample from a subject.
    Type: Application
    Filed: June 18, 2010
    Publication date: June 23, 2011
    Applicant: Whittemore Peterson Institute for Neuro-Immune Disease
    Inventors: Judy A. Mikovits, Vincent Lombardi, Sandra Ruscetti, Francis Ruscetti, Robert Silverman
  • DIAGNOSIS AND TREATMENT OF DISEASES OR DISORDERS ASSOCIATED WITH XENOTROPIC MURINE LEUKEMIA VIRUS
    Publication number: 20110117056
    Abstract: Methods of detecting, diagnosing, monitoring or managing an XMRV-related neuroimmune disease such as chronic fatigue syndrome or XMRV-related lymphoma such as mantle cell lymphoma in a subject are disclosed. These methods comprise determining presence, absence or quantity an XMRV immunopeptide, an XMRV antigen, or an XMRV nucleic acid in a sample from a subject. Therapeutic methods of treatment with anti-retroviral agents are also disclosed. Further disclosed are assays for testing compounds having activity against XMRV.
    Type: Application
    Filed: June 18, 2010
    Publication date: May 19, 2011
    Applicant: Whittemore Peterson Institute for Neuro-Immune Disease
    Inventors: Judy A. Mikovits, Vincent C. Lombardi, Sandra K. Ruscetti, Francis W. Ruscetti