Patents Assigned to William E. Butler and Angiowave Imaging, LLC
  • Patent number: 11123035
    Abstract: The brain appears to have organized cardiac frequency angiographic phenomena with such coherence as to qualify as vascular pulse waves. Separate arterial and venous vascular pulse waves may be resolved. This disclosure states the method of extracting a spatiotemporal reconstruction of the cardiac frequency phenomena present in an angiogram obtained at faster than cardiac frequency. A wavelet transform is applied to each of the pixel-wise time signals of the angiogram. If there is motion alias then instead a high frequency resolution wavelet transform of the overall angiographic time intensity curve is cross-correlated to high temporal resolution wavelet transforms of the pixel-wise time signals. The result is filtered for cardiac wavelet scale then pixel-wise inverse wavelet transformed. This gives a complex-valued spatiotemporal grid of cardiac frequency angiographic phenomena. It may be rendered with a brightness-hue color model or subjected to further analysis.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: September 21, 2021
    Assignee: William E. Butler and Angiowave Imaging, LLC
    Inventors: William E. Butler, Benjamin I. Rapoport