Abstract: A sphincterotome includes a plurality of tines that are longitudinally disposed at a distal end of the sphincterotome. One of the tines is configured as a cutting wire of the sphincterotome and is electrically coupled to an electrical source. The other tines are configured as stabilizing wires to stabilize the cutting wire in a cutting position. In addition, the other tines are electrically insulated from the cutting wire and the electrical source. The plurality of tines are movable between an expanded and a non-expanded configuration. Electrocautery is performed when the tines are in the expanded configuration.

Abstract: An elongate medical device includes a tubular member extending between a proximal end and a distal end that has a wall defining a lumen extending therethrough. The elongate medical device also includes a loop portion comprising a plurality of wires having proximal portions embedded into the wall and distal portions which are connected together to form a loop that is distal the distal end of the tubular member.

Abstract: A sphincterotome having a pair of ribs that are disposed equidistant from each other about an outer surface of a tubular member of the sphincterotome is disclosed. The pair of ribs is oriented perpendicular to a radial direction in which a cutting edge of a cutting wire disposed at a distal portion of the tubular member extends.

Abstract: The present embodiments provide apparatus and methods suitable for coupling a graft member to tissue, closing a bodily opening, and the like. At least one proximal deployable member and at least one distal deployable member are provided, each having a contracted state suitable for delivery and further comprising an expanded state. In the expanded state, the proximal and distal deployable members are configured to secure the graft member to the tissue. Optionally, a loop member may be provided for receiving a suture for further securing the graft member to the tissue.

Abstract: A proximal release delivery system for expandable prostheses includes an elongate catheter, an actuating wire, and a splittable sheath. The actuating wire travels through the lumen of the elongate catheter to the catheter's distal end where it everts about the end of the catheter and travels between the expandable prosthesis and the splittable sheath. A splitter with a blade element is attached to the end of the actuating wire. As an operator pulls the proximal end of the actuating wire in the proximal direction, the splitter travels in the distal direction, splitting the sheath from the proximal to distal end and allowing the prosthesis to expand and deploy. The splittable sheath may also include a longitudinal hinge attached to the expandable prosthesis.

Abstract: A delivery device for proximally releasing an expandable prosthesis and method of use thereof are described. The delivery device comprises an introducer sheath that is capable of distally advancing relative to the endoprosthesis to thereby expose the endoprosthesis from a proximal end thereof. The device is also capable of resheathing over the prosthesis in a proximal direction. The device comprises a drive pulley that can engage a particular gear set to axially move the introducer sheath and proximally release the prosthesis. The drive pulley can also engage another gear set to resheath the introducer sheath and recapture the prosthesis between the inner catheter and the introducer sheath. A directional switch enables the device to operate between the two modes.

Abstract: An external bolster having a main body, a curved portion and a hinge. The bolster also includes a base fixably attached to the main body, the base including a spoke configured to allow air through the base and a cap removably attached to the main body at the hinge, wherein the cap is configured to position a tube along the curved portion of the main body when the cap is in a closed position.

Abstract: A magnet delivery system for forming an anastomosis that comprises a wire guide; a catheter having a delivery portion for advancement into a intracorporeal space, the delivery portion having a lumen extending at least partially therethrough, and a strand connected to the catheter, whereby the magnet is disposed over the wire guide and distal to the catheter, and retained by the strand being releasably connected to the wire guide.

Abstract: A mechanism for sequentially loading and unloading a biopsy instrument includes a first wheel operatively connected with a cannula, the first wheel being rotatably mounted upon an axle such that the axle urges rotation of the first wheel in a first direction to transfer the cannula and the first wheel to a loaded position, the first wheel being configured for selective rotation with respect to the axle in a second direction to transfer the cannula and the first wheel to an unloaded position. A second wheel is operatively connected with a stylet, the second wheel being configured to be rotated by the axle in the first direction when the first wheel is in the loaded position, the second wheel configured for rotation relative to the axle to transfer the stylet and second wheel from the loaded to unloaded position.

Abstract: An endoscope sheath is provided for advancing medical devices into the anatomy of a patient. The endoscope sheath includes at least one lumen that may be used to advance devices alongside an endoscope. The endoscope sheath may include an endoscope cap configured to mate with the lumen. The endoscope may include one or more coupling members configured to mate with the openings of the lumen.

Abstract: Multi-luminal endoscopic systems for sterilely delivering deployable devices. The system comprises an outer catheter comprising a distal portion and a wall that encloses an outer lumen; an inner catheter movably disposed within the outer lumen and having an inner lumen; a balloon-tipped catheter movably disposed within the inner lumen and having a distal portion and a proximal portion, wherein the distal portion of the balloon-tipped catheter comprises a balloon; a deployable device within the outer lumen; an invertible sleeve within the outer lumen with a first section attached to the distal portion of the outer catheter and a second section attached to a push mechanism that is proximal to the deployable device; and wherein the balloon is expandable to contact the invertible sleeve to provide a seal to prevent bodily fluids from entering the outer lumen.

Abstract: A non-expandable stent and a method for implanting the stent are provided. The stent includes a generally tubular body having a lumen defined therethrough. The body includes a proximal portion having a curved portion configured for placement proximal to a sphincter. The body further includes a distal portion having retaining member extending outward from a proximal end of the distal portion. The retaining member is configured for placement distal to the sphincter and for engagement of the sphincter.

Abstract: An ERCP catheter having a removable handle for a lithotriptor compatible basket is disclosed. The removable handle allows the catheter and handle assembly to be removed, leaving the basket in place within the duct and facilitates the use of a lithotriptor for mechanically crushing stone captured in the basket.

Abstract: A system is provided for advancing medical devices along an endoscope to a selected target anatomy in a patient. The advancing system includes a tether having a first portion disposed through a working channel of an endoscope and a second portion disposed external the endoscope. The advancing system may include a guiding device configured to advance a medical device beyond a distal portion of the endoscope to a selected target anatomy.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: A method and device for removing tissue from a patient during a biopsy procedure utilizing a biopsy collection device are provided. The biopsy collection device includes a body portion configured for attachment to an endoscope and a receptacle portion configured to retain a portion of tissue removed from a target site during the biopsy procedure. The biopsy collection device further includes a passageway configured to receive a biopsy sampling device, such as a pair of forceps, passing through the endoscope to the target site.

Abstract: The present embodiments provide apparatus and methods for treating tissue by applying a force to the tissue. In one embodiment, the apparatus comprises a deployable segment having proximal and distal regions, a main body extending therebetween, and a loop member formed at the distal region of the deployable segment. A cannula having a bore is dimensioned to circumferentially surround at least a portion of the main body at a location proximal to the loop member, and a spring member is disposed between the cannula and the loop member. The proximal end of the spring member is affixed to the cannula, and the distal end of the spring member is movable to apply a compressive force to adjust the size of the opening of the loop member and compress tissue disposed within the opening of the loop member. In an alternative embodiment, the cannula is omitted, and a diameter of the loop member is configured to be reduced and increased any number of times before final deployment of the deployable segment.

Abstract: A medical system for performing a tissue biopsy at a remote location within a patient is disclosed. The medical system comprises an elongate outer cutting member, an elongate inner member movably disposed within the outer member, and a tissue traction member for anchoring bodily tissue and pulling a sample of the tissue within the outer cutting member.

Abstract: The present embodiments provide apparatus and methods for facilitating closure of a bodily opening. In one embodiment, a tissue retraction member and a closure member are provided. The tissue retraction member is advanced in a distal direction through the bodily opening in a contracted state, and then expanded at a location distal to the opening. The tissue retraction member then is proximally retracted to engage first and second serosal tissue regions at least partially surrounding the opening, thereby causing the first and second serosal regions to be disposed in an adjacent relationship. The closure member then is deployed around first and second mucosal tissue regions, such that when deployed, the closure member imposes a compressive force to hold the first serosal tissue region in a sealing relationship against the second serosal tissue region to facilitate sealing of the opening.

Abstract: A variety of stent arrangements are described in which multiple stents expand and coordinate to block the spaces between the struts of the outer stent to create a tubular stent not prone to tissue in-growth. One or more stents are selectively positioned within an outer stent such that the struts of the one or more stents at least partially fill the openings of the outer stent. Alternatively, the one or more stents may be permanently affixed to the outer stent to produce a stent arrangement in which the openings between the struts of the outer stent are blocked by the struts of the one or more stents.