Abstract: The urine sampling device has a receptacle 12 with an inlet 14 for receiving a urine discharge. An outlet from the receptacle leads to a detachable sample container 40. The device includes a mechanism operating automatically upon discharge of an initial fraction or urine to open an initially closed flow passage 62 such that a subsequent, middle fraction of urine is conveyed to the sample container. The final fraction of urine is exhausted to waste.