Patents Assigned to Wisconsin Ulumni Research Foundation
  • Method to increase regulatory molecule production
    Patent number: 5587300
    Abstract: The present invention provides a method to increase the production of a regulatory molecule, i.e., a molecule that regulates cell behavior, such as a cytokine or a protooncogene, in a population of transfected cells, whether normal (resting or activated) or tumor cells. The method involves mutating a native or "wild type" cDNA sequence that encodes an mRNA sequence for a regulatory molecule to form a mutant cDNA sequence capable of producing a more stable mRNA sequence.
    Type: Grant
    Filed: April 26, 1994
    Date of Patent: December 24, 1996
    Assignee: Wisconsin Ulumni Research Foundation
    Inventor: James S. Malter