Abstract: Nitrogen containing bicyclic compounds of Formula (I), pharmaceutical compositions comprising these compounds and their use in treating bacterial infection is disclosed.

Abstract: The invention relates to a pharmaceutical composition in the form of an oral film comprising levothyroxine and a film forming polymer. The oral film can be of various types such as and including a mouth dissolving or soluble film, non-mucoadhesive film, fast disintegrating film, buccal film, mucoadhesive film, sublingual film, edible film or wafer. The invention also relates to a process of preparation of such oral film compositions.

Abstract: The invention relates to an autoinjector 59 for administering a fluid medicament to a subject comprising: a housing 1 for receiving a cartridge holder; a driver assembly 8; the driver assembly on actuation may move the cartridge 3 forward in the cartridge holder 2; a needle cover 4 may be coupled to the housing wherein the needle cover 4 travels in a linear or translational movement; said needle cover 4 is adapted to protect a needle when the needle cover may be in first locking position 17 and second locking position 18; the linear or translational movement may be achieved by a cam profile 13 and a cam follower 14; the cam profile 13 may be provided on outside surface of housing and the cam follower 14 located between the needle cover 4 and the housing 1; a first biasing member 15; and a second biasing member 16 configured to bias the cartridge 3 and the needle cover 4 respectively; and a safety cap 11 to control the actuation of the autoinjector.

Abstract: Nitrogen containing bicyclic compounds of Formula (I), pharmaceutical compositions comprising these compounds and their use in treating bacterial infection is disclosed.

Abstract: There is provided a pharmaceutical composition comprising: (a) insulin glargine, (b) at least two amino acids, and optionally (c) one or more pharmaceutically acceptable excipients. In particular, there is provided a pharmaceutical composition comprising: (a) insulin glargine, (b) arginine and isoleucine in a weight ratio of about 1:2, and optionally (c) one or more pharmaceutically acceptable excipients.

Abstract: The invention relates to an autoinjector 59 for administering a fluid medicament to a subject comprising: a housing 1 for receiving a cartridge holder; a driver assembly 8; the driver assembly on actuation may move the cartridge 3 forward in the cartridge holder 2; a needle cover 4 may be coupled to the housing wherein the needle cover 4 travels in a linear or translational movement; said needle cover 4 is adapted to protect a needle when the needle cover may be in first locking position 17 and second locking position 18; the linear or translational movement may be achieved by a cam profile 13 and a cam follower 14; the cam profile 13 may be provided on outside surface of housing and the cam follower 14 located between the needle cover 4 and the housing 1; a first biasing member 15; and a second biasing member 16 configured to bias the cartridge 3 and the needle cover 4 respectively; and a safety cap 11 to control the actuation of the autoinjector.

Abstract: A process for preparing ketolide compounds is disclosed.

Abstract: Pharmaceutical compositions comprising aztreonam or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed.

Abstract: The stable pharmaceutical compositions comprising a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed.

Abstract: Pharmaceutical composition comprising beta-lactamase inhibitors or a pharmaceutically acceptable salt, and a compound of Formula (I) or a pharmaceutically acceptable salt thereof are disclosed.

Abstract: Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

Abstract: A pharmaceutical composition comprising antibacterial agent and tazobactam, wherein the ratio of tazobactam to the antibacterial agent in the composition is in the range of from about 0.5 to about 2 gram of tazobactam per gram of the antibacterial agent, are disclosed.

Abstract: Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

Abstract: Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed.

Abstract: Compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, their preparation, pharmaceutical compositions comprising such compounds and their use in treating and/or preventing bacterial infections are disclosed.

Abstract: The lyophilized solid pharmaceutical compositions comprising a compound of Formula (I) or a stereoisomer or a pharmaceutically acceptable derivative thereof are disclosed.

Abstract: The invention relates to a trainer device for an autoinjector, comprising: a housing; a collet holder comprising a track; a safety cap removably connected to the collet holder; a cover member; a flex stem having flex arm; a cover member locking mechanism; and a resetting mechanism. The cover member further comprises a plastic sleeve or an elastomeric sleeve to prevent or inhibit the obstruction of the movement of cover member when the user accidentally holds the cover member during the actuation of trainer device.

Abstract: It may be one of the aspects of the invention that a drug delivery device for delivery of two or more independently user selectable multiple doses of medicaments contained in separate cartridges of the medicament reservoirs within a single device operatively connected to a single dispense interface which may be operatively connected to a single activation button; It may be another aspect of the invention that unlocking of the user operable variable dose locking mechanism of the drug delivery device may be easily carried out by one hand operation by a lock slider unlock by the user.

Abstract: The fluid delivery pen of the present invention has a reduced dose setting friction mechanism which may produce a sound of higher audibility for each click corresponding to one unit dose set using a dose setting mechanism and also produces a sound of lower audibility than the former for each click when the set dose is reduced using the dose setting mechanism. The fluid delivery pen driving mechanism of the present invention has an indication to an end of dose of fluid in a cartridge.

Abstract: A pharmaceutical compositions comprising: (a) a carbapenem antibacterial agent selected from imipenem, meropenem, ertapenem, doripenem or a pharmaceutically acceptable derivative thereof, and (b) a compound of Formula (I), or a stereoisomer or a pharmaceutical acceptable derivative thereof, are disclosed.