Patents Assigned to Women and Infants Hospital of RI, Inc.
  • Compositions and methods for cancer treatment
    Patent number: 8853188
    Abstract: Bromoacetoxycalcidiol (B3CD), which is structurally related to calcidiol, exhibits cytotoxic and apoptotic activity toward cancer cells, including highly aggressive neuroblastoma cells. A series of small molecules designed around the structure of B3CD is expected to have growth inhibitory and apoptogenic activities toward a wide range of malignancies. B3CD shows no apparent toxicity in vivo, indicating potential value as a chemotherapeutic agent which will be particularly useful in treating highly aggressive tumors.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: October 7, 2014
    Assignee: Women and Infants Hospital of RI, Inc.
    Inventor: Narasimha Swamy
  • Compositions and Methods for Cancer Treatment
    Publication number: 20100144671
    Abstract: Bromoacetoxycalcidiol (B3CD), which is structurally related to calcidiol, exhibits cytotoxic and apoptotic activity toward cancer cells, including highly aggressive neuroblastoma cells. A series of small molecules designed around the structure of B3CD is expected to have growth inhibitory and apoptogenic activities toward a wide range of malignancies. B3CD shows no apparent toxicity in vivo, indicating potential value as a chemotherapeutic agent which will be particularly useful in treating highly aggressive tumors.
    Type: Application
    Filed: March 3, 2006
    Publication date: June 10, 2010
    Applicant: Women and Infants Hospital of RI, Inc.
    Inventors: Narasimha Swamy, Hema Malini K. Sundaresha