Patents Assigned to Worcester Polytechnic Institute
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Patent number: 12280177Abstract: Decellularized plant tissues and the use of these plant tissues as scaffolds are disclosed herein. Particularly, decellularized plant tissues are functionalized such to allow for human cell adhesion, thereby allowing for their use as scaffolds for human cells. These scaffolds can then be used in a number of applications/markets, including as research tools for tissue engineering, regenerative medicine, and basic cellular biology.Type: GrantFiled: July 29, 2021Date of Patent: April 22, 2025Assignees: Wisconsin Alumni Research Foundation, ARKANSAS STATE UNIVERSITY—JONESBORO, Worcester Polytechnic InstituteInventors: William L. Murphy, Gianluca Fontana, Joshua Gershlak, Glenn Gaudette, Pam Weathers, Tanja Dominko, Marsha Rolle, Sarah Hernandez, Carol Cramer, Luis Fabircio Medina-Bolivar, Bernard Binder
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Patent number: 12209806Abstract: An atomizing spray dryer employs one or more stages defined by ultrasonic transducers in close proximity to a liquid feed opening forming a path of an atomization flow for producing uniform droplets from a close tolerance with the transducer. The atomization flow exits a gap between the transducer and an outer edge of the opening, such that the passed liquid is responsive to an oscillation of the transducer for forming the droplets. A conical or other suitably shaped transducer engages a substantially round liquid feed opening. Subsequent stages may include a circular, ring, or other suitable shape aligned to receive the atomization flow from a circumference of the conical base, or may also take any suitable shape, preferably to receive droplets directed by the first stage.Type: GrantFiled: January 31, 2023Date of Patent: January 28, 2025Assignee: Worcester Polytechnic InstituteInventors: Jamal S. Yagoobi, Mengqiao Yang, Mehrnoush F. Dardashti
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Publication number: 20250028784Abstract: Embodiments of the present innovation relate to a Fourier dot product analog matrix multiplier device. In one arrangement, the analog matrix multiplier device is configured as a set of analog transistor circuits and can include a set of signal generators and a Fourier dot product circuit. The components of the analog matrix multiplier device are configured to perform a Fourier dot product multiplication process relative to coefficients received by the analog matrix multiplier device. The Fourier dot product analog matrix multiplier device leverages the low power capabilities of analog circuits and a mathematical algorithm to reduce the number of components and power required to perform matrix multiplication.Type: ApplicationFiled: July 19, 2024Publication date: January 23, 2025Applicant: Worcester Polytechnic InstituteInventors: Jack Adiletta, Ukluhan Guler
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Publication number: 20240423550Abstract: A concussion detection system comprises a kinematic detection device configured to be carried by a head of a user and a concussion detection device disposed in electrical communication with the kinematic detection device. The concussion detection device comprises a controller configured to: receive kinematic data from the kinematic detection device, the kinematic data associated with a head impact of the user, apply the kinematic data to a strain prediction engine to generate a strain identifier associated with the head impact and a concussion risk assessment associated with the strain identifier, and output the concussion risk assessment based upon the strain identifier and configured to identify a concussion risk associated with the head impact. The concussion detection device can assess concussion risk in the user for an individual impact, or based on a history of multiple head impacts, and can further take into account head or brain size differences.Type: ApplicationFiled: March 7, 2024Publication date: December 26, 2024Applicant: Worcester Polytechnic InstituteInventors: Songbai JI, Shaoju WU
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Patent number: 12145013Abstract: A volatile liquid storage container has combustion resistance properties from a flexible sock or tube constructed of fire resistant fibers coupled to a neck of the storage container to prevent flame flash-back into the storage container. The storage container defines an enclosed volume having an orifice in the container material leading to a neck for pouring and filling the enclosed volume for exchanging the contents therein. The tube is elongated and surrounds a circumference of the orifice for engaging any ignition source entering through the orifice. The flexible nature of the tube or sock allows it to extend to an opposed interior surface of the enclosed volume, and ensures that the tube or sock is immersed in the fluid for encircling any ignition path to the volatile liquid without interfering with an ability to pour or refill the container.Type: GrantFiled: March 31, 2017Date of Patent: November 19, 2024Assignee: Worcester Polytechnic InstituteInventors: Brian E. Elias, Robert G. Zalosh, Ali S. Rangwala, Samim Safaei Boroojeny, Larry Genovesi
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Publication number: 20240324922Abstract: A health experience detection system comprises an eye-tracking device and a health experience detection device disposed in electrical communication with the eye-tracking device. The health experience detection device comprises a controller having a memory and a processor. The controller is configured to: receive eye-movement data from the eye-tracking device, the eye-movement data associated with eye-movement of a user and comprising at least one of saccade event data and fixation event data, apply the eye-movement data to a health experience identification engine to generate a health experience identifier associated with the user, and output a notification regarding the health experience identifier of the user as associated with the eye-movement data.Type: ApplicationFiled: February 22, 2024Publication date: October 3, 2024Applicant: Worcester Polytechnic InstituteInventors: Soussan Djamasbi, Javad Norouzi Nia, Doaa Alrefaei, Diane Strong, Randy Paffenroth
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Publication number: 20240324862Abstract: An endoscopic system may include an endoscope including a handle and an elongate shaft extending distally therefrom. The handle may include a non-motorized and non-ratcheting actuation mechanism configured to articulate a distal tip portion of the elongate shaft. The distal tip portion may be articulatable in response to a manually applied force exerted upon the actuation mechanism. Removal of the manually applied force may lock the distal tip portion in its then-current configuration. The non-motorized and non-ratcheting actuation mechanism may include a clutch mechanism actuatable in response to an electrical signal generated in response to sensing a user-applied force to the actuating mechanism by a strain gauge.Type: ApplicationFiled: June 4, 2024Publication date: October 3, 2024Applicants: BOSTON SCIENTIFIC SCIMED, INC., WORCESTER POLYTECHNIC INSTITUTEInventors: CHRISTOPHER J. NYCZ, ELIZABETH M. ALBRECHT, MEGAN CHROBAK, KIANOOSH GHAZI, GREGORY SCOTT FISCHER, BRYAN ALLEN CLARK
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Publication number: 20240307005Abstract: This disclosure relates to systems and processes for estimating blood pressure. Systems described herein comprise at least one sensor for measuring at least one waveform related to blood pressure from a patient; at least one processor; and at least one computer-readable storage medium having encoded thereon executable instructions to carry out a method comprising: receiving, from the at least one sensor, the at least one waveform and determining one or more features comprising at least one or more temporal features and one or more morphology features; and analyzing the one or more features using one or more trained models to determine one or more blood pressure (BP) value associated with the patient; and outputting the one or more BP value determined for the patient based on the received one or more features. The system allows for continuous and noninvasive calculations of a blood pressure to the patient or other users.Type: ApplicationFiled: March 14, 2024Publication date: September 19, 2024Applicant: Worcester Polytechnic InstituteInventors: Rajesh S. Kasbekar, Edward A. Clancy
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Patent number: 12082979Abstract: A surgical head clamp and robotics platform secures a head of a patient and positions an instrument relative to the head for a medical procedure. The head clamp and robotics platform comprises a planar C-shaped frame for at least partially encircling the head of a patient. An instrument arm is mounted is to a free distal end of one arm member of the frame. The instrument arm extends away from the arm member in a direction transverse to the plane of the frame. The instrument arm includes a base mounted to the arm member for movement along three degrees of freedom relative to the frame, a proximal portion extending from and pivotally connected to the base, and a distal instrument holder extending from and pivotally connected to the proximal portion. The instrument arm functions to selectively position the instrument in an angular position relative to the head clamp.Type: GrantFiled: October 12, 2021Date of Patent: September 10, 2024Assignee: Worcester Polytechnic InstituteInventors: Gregory S. Fischer, Benjamin Piecuch, Dino Kasvikis, Perry A. Genova
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Patent number: 12074302Abstract: Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.Type: GrantFiled: June 15, 2022Date of Patent: August 27, 2024Assignee: Worcester Polytechnic InstituteInventors: Yan Wang, Eric Gratz, Qina Sa, Zhangfeng Zheng, Joseph Heelan, Kee-Chan Kim
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Patent number: 12055381Abstract: A strain gauge device employs a reflective base adapted to reflect a divergent optical signal, and a glass tube attached to the reflective base for optical communication therewith, the glass tube having a working length into which an optical fiber is inserted. The optical fiber is configured for transporting an optic signal indicative of the detected strain. The optic fiber has an outside diameter slightly smaller than an inside diameter of the glass tube for providing a slight tolerance. A distal end is disposed in slidable communication with an interior of the glass tube and accommodated by the tolerance, and a sensing circuit at the proximate end receives an optical signal indicative of strain or displacement. A resilient buffer layer made of soft silicone is disposed outside the glass tube to allow for large deformation measurements and reduce the distortion of the deformation by the introduction of the sensor.Type: GrantFiled: February 10, 2022Date of Patent: August 6, 2024Assignee: Worcester Polytechnic InstituteInventors: Yuxiang Liu, Hamed Jafarishad, Mucheng Li
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Patent number: 12049409Abstract: Bauxite residue recovery includes mixing a solution of hydrochloric acid (HCL) according to a predetermined concentration, and adding the HCL solution to a quantity of raw red mud recovered from industrial operations as waste material. The highly alkaline property of the bauxite residue, commonly known as red mud is at least partially neutralized from the HCL, and makes the resulting washed red mud more amenable to subsequent uses in various applications in fields such as construction, wastewater treatment, and metal recovery processes. The process recovers washed red mud from the red mud and HCL solution by filtering the raw red mud and HCL solution for generating a stream of leach liquor from the filtrate and the recovered washed red mud from the residue.Type: GrantFiled: December 10, 2021Date of Patent: July 30, 2024Assignee: Worcester Polytechnic InstituteInventors: Himanshu Tanvar, Brajendra Mishra
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Patent number: 12046725Abstract: Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.Type: GrantFiled: February 23, 2023Date of Patent: July 23, 2024Assignee: Worcester Polytechnic InstituteInventors: Yan Wang, Diran Apelian, Haiyang Zou
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Patent number: 12035887Abstract: An endoscopic system may include an endoscope including a handle and an elongate shaft extending distally therefrom. The handle may include a non-motorized and non-ratcheting actuation mechanism configured to articulate a distal tip portion of the elongate shaft. The distal tip portion may be articulatable in response to a manually applied force exerted upon the actuation mechanism. Removal of the manually applied force may lock the distal tip portion in its then-current configuration. The non-motorized and non-ratcheting actuation mechanism may include a clutch mechanism actuatable in response to an electrical signal generated in response to sensing a user-applied force to the actuating mechanism by a strain gauge.Type: GrantFiled: November 22, 2021Date of Patent: July 16, 2024Assignees: BOSTON SCIENTIFIC SCIMED, INC., WORCESTER POLYTECHNIC INSTITUTEInventors: Christopher J. Nycz, Elizabeth M. Albrecht, Megan Chrobak, Kianoosh Ghazi, Gregory Scott Fischer, Bryan Allen Clark
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Patent number: 12017410Abstract: A nozzle apparatus for a 3D printer employs a center post or shape and extrudes a circumferential, tubular form having a central void. The nozzle includes a radial arrangement of prongs or supports around a center post, which provides space for molten print medium to flow in a 360° form around the center post. The nozzle extrudes a hollow tubular form around the post that can lay a tube shaped article on a perpendicular print bed, or can be used to deposit high resolution, hollow cylindrical segments for forming lightweight articles with less volume of print medium required due to the hollow extruded shape. A stream of air or gas may be emitted into the center of the extrusion for maintaining a tubular shape. Other suitable shapes may be employed by altering the contour of the center post and the bore.Type: GrantFiled: October 16, 2023Date of Patent: June 25, 2024Assignee: Worcester Polytechnic InstituteInventors: Ethan R. Wilke, Loris Fichera, Nicholas E. Pacheco
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Publication number: 20240192198Abstract: This disclosure relates generally to biomimetic proteoliposomes, a method of making and a method of using the same. In particular, this disclosure provides proteoliposomes comprising one or more phospholipid carrier and one or more protein embedded in the one or more phospholipid carrier, wherein the one or more phospholipid carrier comprises a phospholipid composition with similar proportions of phospholipids as a naturally occurring cell type and a phospholipid concentration of about 1-50 mM; and wherein the one or more protein comprises a protein composition with similar proportions of proteins as the naturally occurring cell type.Type: ApplicationFiled: November 13, 2023Publication date: June 13, 2024Applicant: Worcester Polytechnic InstituteInventors: Christina M. Bailey-Hytholt, Daniel Zimmer
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Patent number: 11961626Abstract: A fiber optic based particle manipulation system employs one or more optical fibers for emanating a refracted optical manipulation signal directed at a target particle for fixing or manipulating the particle for examination, research and manufacturing. A target particle may be a living cell or inanimate sample or compound of matter. An alignment linkage controls optical fibers carrying the manipulation signal for focusing one or more manipulation signals on the target particle. Manipulated particles occupy a fluid medium of either liquid or gas, and are responsive to the manipulation signal based on both photon bombardment and temperature differential from photon contact. The temperature differential is based on surface properties of the target particle, as smooth particles tend to exhibit a greater thermal differential for stronger displacement forces driving or affecting the target particle.Type: GrantFiled: January 26, 2022Date of Patent: April 16, 2024Assignee: Worcester Polytechnic InstituteInventors: Yuxiang Liu, Chaoyang Ti, Qi Wen
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Patent number: 11955613Abstract: Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution.Type: GrantFiled: August 26, 2021Date of Patent: April 9, 2024Assignee: Worcester Polytechnic InstituteInventors: Yan Wang, Eric Gratz, Qina Sa, Zhangfeng Zheng, Joseph Heelan, Kee-Chan Kim
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Patent number: 11955618Abstract: A metal-air battery and methods for generating electricity in a metal-air battery are described herein. The battery and the method includes heating an anhydrous salt to obtain a molten salt electrolyte; contacting the molten salt electrolyte to at least one cathode communicating with air; reducing air at the cathode to obtain oxygen ions for diffusing through the molten salt electrolyte; oxidizing at least one metal anode by the oxygen ions in the electrolyte thereby generating electricity and forming a metal anode oxide; and cooling at least one section of the metal-air battery for precipitating the metal anode oxide.Type: GrantFiled: March 16, 2022Date of Patent: April 9, 2024Assignee: Worcester Polytechnic InstituteInventors: Adam C. Powell, Hongyi Sun, Mahya Shahabi, Yu Zhong
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Patent number: 11925358Abstract: A surgical rongeur device has an interchangeable, locking tip at a cutting end for engageable replacement with a variety of cutting tips for facilitating sterilization and blade changes. A detachable linkage between a handle portion and an interchangeable cutting tip (tip) provides a strong connection for actuation by the handle end but allowing for tip replacement via slidable, lateral displacement of the tip. The tip includes a blade and footplate formed from an amorphous metal for longevity and strength advantages. A handle provides a lever to actuate the tip from slidable communication via the detachable linkage. An interlocking member extends longitudinally from the handle into an internal slot on the tip for locking the tip by preventing lateral movement out of alignment with the handle. The aligned tip is responsive to actuation from the handle via a rail for disposing the blade longitudinally against the footplate.Type: GrantFiled: April 29, 2021Date of Patent: March 12, 2024Assignee: Worcester Polytechnic InstituteInventors: Jesse Kauffman, Karim A. Tarabein, Cameron W. Downey