Abstract: Cannula devices and related methods are provided. In accordance with one embodiment, a cannula ring includes a body portion having a substantially cylindrical member defining an opening therethrough. A plurality of anchor arms coupled with the body portion and configured to be positioned in a first, collapsed state and a second, deployed state, wherein the anchor arms each include a free end that is radially displaced from the body portion while in the second, deployed state relative to their positions while in the first, collapsed state. Suture rings and other associated structures and devices are also described.

Abstract: A system configured to predict characteristics of an artificial heart is described. The system includes a processor and memory in electronic communication with the processor, and an artificial neural network configured to receive an input vector of a predetermined length to train the artificial neural network, produce an output vector based on the input vector, and compare the output vector with a target vector of the predetermined length. When the output vector does not match the target vector within a predetermined error rate, the network is configured to adjust at least one weight, and when the output vector matches the target vector within the predetermined error rate, the network is configured to execute the input vector to produce an estimate at least one characteristic of the artificial heart.

Abstract: A system configured to predict characteristics of an artificial heart is described. The system includes a processor and memory in electronic communication with the processor, and an artificial neural network configured to receive an input vector of a predetermined length to train the artificial neural network, produce an output vector based on the input vector, and compare the output vector with a target vector of the predetermined length. When the output vector does not match the target vector within a predetermined error rate, the network is configured to adjust at least one weight, and when the output vector matches the target vector within the predetermined error rate, the network is configured to execute the input vector to produce an estimate at least one characteristic of the artificial heart.

Abstract: There are disclosed systems and methods of determining a fault location on a wire. In an embodiment, a system includes a PN code having a chip-time. Software code is provided for delaying the PN code a series of delays to form delayed PN samples, a sum of the series of delays being less than one chip-time. Software code is provided for summing the delayed PN samples with the PN code to form a summed sequence. Software code is provided for transmitting the summed PN sequence to the wire. Software code is provided for receiving a signal from the wire related to the summed PN sequence. Software code is provided for mixing the signal received from the wire with a delayed copy of the summed PN sequence so as to form a mixed signal. Software code is provided for integrating the mixed signal to map faults. Other embodiments are also disclosed.

Abstract: A pump with magnetically-levitated rotor includes a position sensor having an eddy-current sensor coil that operates as a resonating element in a low frequency oscillator located within the pump housing. The oscillator is operably interconnected with additional electronics that shift the frequency of the oscillator output signal to a lower frequency. The lower frequency signal is directed to a frequency measurement circuit that provides a value representing a position of the rotor.

Abstract: Cannula devices and related methods are provided. In accordance with one embodiment, a cannula ring includes a body portion having a substantially cylindrical member defining an opening therethrough. A plurality of anchor arms coupled with the body portion and configured to be positioned in a first, collapsed state and a second, deployed state, wherein the anchor arms each include a free end that is radially displaced from the body portion while in the second, deployed state relative to their positions while in the first, collapsed state. Suture rings and other associated structures and devices are also described.

Abstract: There are disclosed apparatus and methods for replacing a percutaneous cable in connection with a vascular device. In an embodiment, the apparatus includes a distal disconnect coupler, a distal connector portion of the cable configured for removable connection with the distal disconnect coupler, and a connector cap configured for removable connection with the distal disconnect coupler and for tunneling through skin and tissue. In one embodiment, a method of repositioning a percutaneous cable in connection with a vascular device includes providing the cable with a distal disconnect coupler, disconnecting the cable at the distal disconnect coupler, attaching a connector cap to the distal disconnect coupler, removing the percutaneous cable from a first exit site, tunneling the connector cap together with the distal disconnect coupler through skin and tissue to form a new exit site, disconnecting the connector cap, and connecting the cable to the distal disconnect coupler.

Abstract: A system configured to predict characteristics of an artificial heart is described. The system includes a processor and memory in electronic communication with the processor, and an artificial neural network configured to receive an input vector of a predetermined length to train the artificial neural network, produce an output vector based on the input vector, and compare the output vector with a target vector of the predetermined length. When the output vector does not match the target vector within a predetermined error rate, the network is configured to adjust at least one weight, and when the output vector matches the target vector within the predetermined error rate, the network is configured to execute the input vector to produce an estimate at least one characteristic of the artificial heart.

Abstract: A method and apparatus for remotely cannulating a body part are disclosed. The apparatus is an endoscopic cannulation apparatus having a fluid stasis assembly and a coring assembly. The fluid stasis assembly allows for the penetration of the body part and deployment of an occlusive device to prevent the escape of fluid during the coring and cannulation of the body part. The cannulation assembly allows for the coring of the body part without the introduction of air bubbles or other embolic materials into the patient. The method of the invention provides for the remote coring and cannulation of a body part such as a heart, blood vessels, the stomach, intestines, and other body parts with a sealed apparatus that may be de-aired to lessen the risk of the introduction of emboli into a system.

Abstract: A remote cannulation assembly is disclosed for rapidly cannulating a body part such as a heart during a medical procedure. Cannulation is often conducted in procedures such as the installation of a ventricular assist device. The cannulation assembly of the invention utilizes an isolation valve to create a sealed fluid environment for the procedure. The invention further includes a coring assembly that may be used with the cannulation apparatus. Methods of cannulating a heart or other body part are also disclosed in which the risk of emboli is reduced. Additionally, methods of connecting and disconnecting two fluid conducting elements are disclosed.

Abstract: A rotordynamic pump for delivering continuous flow of fluids, such as blood, is provided. In one embodiment, the pump includes a stator housing having an inlet and an outlet. A rotor hub is disposed within the stator housing having a first, mixed-stage impeller and a second, axial-flow stage impellers. One or more stator vanes and extend radially inwardly from the stator housing. In one particular embodiment, the second stage impeller is disposed nearer to the outlet than to the inlet. The stator vanes may include a first set of stator vanes disposed between the first and second stage impellers, and a second set of stator vanes positioned between the second stage impellers and the outlet.

Abstract: A rotordynamic pump for delivering continuous flow of fluids, such as blood, is provided. In one embodiment, the pump includes a stator housing having an inlet and an outlet. A rotor hub is disposed within the stator housing having a mixed-stage or mixed-flow impeller. The mixed flow impeller includes both principle blades and splitter blades, the splitter blades exhibiting a shorter axial length than the principle blades. One or more stator vanes and extend radially inwardly from the stator housing. The splitter blades and principle blades are arranged in a circumferentially alternating pattern. The stator vanes include principle stator vanes and splitter stator vanes, the splitter stator vanes exhibiting a shorter axial length than the principle stator vanes. The splitter vanes and principle vanes are arranged in a circumferentially alternating pattern. The rotor hub may be magnetically suspended and rotated within the stator housing.

Abstract: A pumping system for assisting either or both ventricles of the heart. In one embodiment, separate devices are provided for each ventricle. In another embodiment, one device provides both right and left pumping. The pumping system is small, efficient, atraumatic, and fully implantable. In addition, the pumping system can provide pulsatile flow during systole. The ventricular assist device includes an actuator plate between a pair of serially connected pumping chambers that operate in a two-stroke mode, specifically a power stroke and a transfer stroke. The ventricular assist device also includes an electromagnetic drive system that provides adjustment to the pump pressure according to the current through an electromagnet. For the pumping system, springs provide a “spring force” on the actuator plate that is towards the high-pressure pump chamber.

Abstract: A method and apparatus for controlling a ventricular assist device are disclosed. The method includes the step of providing a ventricular assist device which can be defined in terms of operational parameters such as pump speed or current. Measuring at least one physiological parameter reflecting a physiological state corresponding to a patient. Correlating at least one physiological parameter measured from the patient to at least one operational parameter using an estimation method. Selecting a physiological state definable by desired values of the physiological parameters. Monitoring at least one operational parameter. Controlling input values of the operational parameter based on output from the monitoring step. The apparatus includes a pump driven by a motive drive and having an impeller. A sensor detects the value of an operational parameter of the pump.

Abstract: An inflow conduit assembly for conducting blood from a ventricle to a Ventricular Assistance Device (VAD) is provided. The assembly includes a rigid tube including an angled heart engaging end for insertion into a ventricle. The angled heart engaging end defines a long side for placement adjacent a heart septum. The tube includes an orifice end for attachment to the VAD, and the inflow conduit assembly further includes a coupling for attaching the orifice end of the tube to the VAD. The coupling is movable between a rotatable position wherein the tube is rotatable relative to the VAD, and a locked position wherein the tube is immobile relative to the VAD.

Abstract: An implantable ventricular assist device (VAD) has a small size to provide full-implantable capabilities. The VAD has two variable-volume chambers and an actuator for expelling blood from the chambers in sequence and to a common outlet, thus operating as a positive-displacement pump. The variable-volume chambers may be flexible sacs and the pump is operable at a substantially continuous flow, such as during the systolic phase of the assisted ventricle. A method of operation includes operating the pump at a first frequency during systole and a second lower frequency during diastole. The VAD pump includes a pair of coils housed within a frame and disposed in a spaced relationship to generate a coil flux through a pair of poles. A plate including an armature and a magnet is disposed within the frame such that the armature is between the poles and the magnet is between the coils. Gaps are defined between the armature and each of the poles and the coil flux displaces the armature across the gap.