Abstract: A high-concentration sewage treatment system for self-sufficiency of energy is provided. The system includes a hydrolysis acidification device, an anaerobic reactor, a sludge treatment device, a desulfurization tower, and a biogas power generation device. The hydrolysis acidification device includes a hydrolysis acidification tank, a first sedimentation tank, a first overflow water tank and an overflow pipe. The sludge treatment device includes a second sedimentation tank, a second overflow water tank, an inlet pipe and a dissolved oxygen meter. The second overflow water tank communicates with the hydrolysis acidification tank through a return pipe. The inlet pipe defines a jet hole. A regulating valve is connected to the inlet pipe. The regulating valve controls a speed and a height of mixed liquid in the jet hole. A high-concentration sewage treatment method for self-sufficiency of energy is also provided.