Patents Assigned to Wyeth and Imperial College Innovations Limited
  • Compositions and methods for treating rage-associated disorders
    Publication number: 20060140933
    Abstract: Fusion proteins comprising a Receptor for Advanced Glycation End Products Ligand Binding Element (RAGE-LBE) and an immunoglobulin element are disclosed. Also disclosed are fusion proteins comprising a RAGE-LBE and a dimerization domain. Also disclosed are nucleic acids encoding such fusion proteins and methods for using disclosed nucleic acids and proteins to, for example, treat RAGE-related disorders. Additional compositions and methods are also disclosed.
    Type: Application
    Filed: August 18, 2003
    Publication date: June 29, 2006
    Applicant: Wyeth and Imperial College Innovations Limited
    Inventors: Debra Pittman, Brian Clancy, Glenn Larsen, William Trepicchio, Fionula Brennan, Marc Feldmann, Brian John Foxwell, Jeffrey Feldman