Patents Assigned to XCR Diagnostics, Inc.
  • Chemical indicator device with heat blocks
    Patent number: 11293855
    Abstract: A chemical indicator device comprising a housing that comprises a viewing port, a means to provide illumination, and test tube wells so configured such that the observer views the test tubes from the side.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: April 5, 2022
    Assignee: XCR Diagnostics, Inc.
    Inventors: Brian Caplin, Nicole A. Fugere
  • MULTIPLEX PROBES
    Publication number: 20200172958
    Abstract: Methods and reagents suitable for conducing polymerase chain reaction are described. In particular, the disclosure provides probes and primers that are suitable in dynamic flux amplification procedures. In aspects, the disclosure provides long oligonucleotide probes and primers, as well as triplex forming probes and primers, which function within the narrow Tm ranges used with dynamic flux amplification. However, embodiments are also provided wherein the probes and primers taught herein can be utilized in standard PCR.
    Type: Application
    Filed: July 3, 2019
    Publication date: June 4, 2020
    Applicant: XCR Diagnostics, Inc.
    Inventor: Brian Caplin
  • DNA amplification technology
    Patent number: 10669574
    Abstract: Methods and reagents suitable for conducing polymerase chain reaction are described. In particular, a nucleic acid amplification design strategy and thermal cycling profile to enable efficient amplification of multiple nucleic acid targets along with improved sensitivity is disclosed. The present disclosure also describes methods and devices for increasing the melting temperature (Tm) of a primer.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 2, 2020
    Assignee: XCR Diagnostics, Inc.
    Inventors: Brian Caplin, Bryson Green
  • DYNAMIC FLUX NUCLEIC ACID SEQUENCE AMPLIFICATION
    Publication number: 20190271036
    Abstract: Provided herein are dynamic flux nucleic acid sequence amplification methods. The dynamic flux nucleic acid sequence amplification methods described herein are capable of amplifying nucleic acid sequences within a narrow temperature range. In some aspects, the disclosure provides for real-time dynamic flux nucleic acid sequence amplification methods.
    Type: Application
    Filed: May 17, 2019
    Publication date: September 5, 2019
    Applicant: XCR Diagnostics, Inc.
    Inventor: Brian Erich CAPLIN