Patents Assigned to Xenotech Incorporated
  • Directed switch-mediated DNA recombination
    Patent number: 5714352
    Abstract: Switch regions derived from an immunoglobulin (Ig) gene are used to direct recombination between a targeting construct containing a promoter, a switch region (S.sub.1), and 2) a target locus minimally containing a promoter, a switch region (S.sub.2), and a target sequence.
    Type: Grant
    Filed: March 20, 1996
    Date of Patent: February 3, 1998
    Assignee: Xenotech Incorporated
    Inventor: Aya Jakobovits
  • Method to ameliorate osteolysis and metastasis
    Patent number: 5626845
    Abstract: Materials immunoreactive with parathyroid hormone-related protein (PTH-rp) are used in the invention method to prevent and treat metastasis and cancer cell growth in bone as well as osteolysis and symptomatic sequelae thereof. Humanized antibodies are included in the invention for application of the invention method to human subjects.
    Type: Grant
    Filed: January 23, 1995
    Date of Patent: May 6, 1997
    Assignee: Xenotech Incorporated
    Inventors: Toshiyuki Yoneda, Gregory R. Mundy