Abstract: The present application proposes a method for detecting an okadaic acid based on a near-infrared photoelectric composite material, which includes the following steps: synthesizing NaYF4: Yb, Tm up-conversion nanoparticles (UCNPs) and a semiconductor material flower-like tungsten oxide (WO3) by a simple high-temperature solvothermal method; coupling the UCNPs with an okadaic acid monoclonal antibody through a classic amidation reaction to construct a competitive near-infrared photoelectrochemical immunosorbent assay (cNIR-PECIA) for okadaic acid detection. In addition, the present application employs a screen-printed carbon electrode (SPE) as the working electrode, and thus only requires a small amount of electrolytes, which is low-cost and maintenance-free.
Type:
Grant
Filed:
October 21, 2021
Date of Patent:
November 28, 2023
Assignees:
JiMei University, Xiamen Center for Disease Control and Prevention
Inventors:
Xiaomei Chen, Chenyan Zheng, Mingming Yin, Bingyuan Su, Jie Wei
Abstract: The present application proposes a method for detecting an okadaic acid based on a near-infrared photoelectric composite material, which includes the following steps: synthesizing NaYF4: Yb, Tm up-conversion nanoparticles (UCNPs) and a semiconductor material flower-like tungsten oxide (WO3) by a simple high-temperature solvothermal method; coupling the UCNPs with an okadaic acid monoclonal antibody through a classic amidation reaction to construct a competitive near-infrared photoelectrochemical immunosorbent assay (cNIR-PECIA) for okadaic acid detection. In addition, the present application employs a screen-printed carbon electrode (SPE) as the working electrode, and thus only requires a small amount of electrolytes, which is low-cost and maintenance-free.
Type:
Application
Filed:
October 21, 2021
Publication date:
June 16, 2022
Applicants:
JiMei University, Xiamen Center for Disease Control and Prevention
Inventors:
Xiaomei CHEN, Chenyan ZHENG, Mingming YIN, Bingyuan SU, Jie WEI