Abstract: A kit for enabling delivery of an active compound to the skin for penetration into the skin, a delivery device for delivering an active compound, and a method of delivery of an active compound are provided. An active compound delivery kit for enabling delivery of an active compound into the skin of a subject includes an arrangement for providing a pathway into a biological barrier of a subject in an application zone, an active compound provided in dry form, and a delivery device for delivery of dissolved active compound to the application zone. Provision of a pathway into the biological barrier, preferably skin, is provided and the active compound applied in optimum form within a short time frame after forming the pathway ensuring treatment of the desired skin cells is optimised.

Abstract: A device that may be placed on a biological barrier can be used to perforate the biological barrier for a variety of purposes such as cosmetic, scar treatment or for the delivery of active agents. A flexible substrate has a first side and a second opposing side and a plurality of micro-penetrator arrangements each comprising a head and a first and second projection, for penetrating a biological barrier, extending from the head. The first and second projection at least partially extend through the flexible substrate towards the first side. The head comprises an elongate arm for spacing apart the first and second projections. A force is applied to the second side causing flexing of the flexible substrate and pushing the projections into communication with a biological barrier.