Abstract: The present invention relates generally to derivatized antifungal compounds that are peptide-based constructs derived from or based on subsequences of Domain III (amino acids 142-169) of bactericidal/permeability-increasing protein (BPI) and in vivo or in vitro uses of such compounds.
Type:
Grant
Filed:
June 25, 1999
Date of Patent:
March 12, 2002
Assignee:
Xoma (US) Technology Ltd.
Inventors:
Roger G. Little, II, Jong-Jye Lin, J. G. Kinyua Gikonyo