Patents Assigned to XOMICS BIOPHARMA, INC.
  • Methods of preventing toxicity of platinum drugs
    Patent number: 11197862
    Abstract: Methods for reducing platinum drug-induced toxicity in a cell expressing Organic Cation Transporter 2 (OCT2), methods for reducing platinum drug-induced toxicity in a subject, methods for treating cancer, methods for increasing efficacy of platinum drug treatment in a subject, and pharmaceutical compositions are described. The described methods and compositions include an OCT2 inhibitor where the OCT2 inhibitor is buflomedil or a salt thereof, dolutegravir or a salt thereof contains an imidazole, or is miconazole or a salt thereof.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: December 14, 2021
    Assignee: XOMICS BIOPHARMA, INC.
    Inventors: Yong Huang, Dominique P. Bridon, Xuexiang Zhang, Chien-Ming Li