Abstract: The present invention relates generally to an eco-friendly methodology for the conversion of alcohols and aldehydes to amines and amides using an integrated enzyme cascade system with metal- and organocatalysis. More specifically, the present invention relates to synthesis of capsaicinoids starting from vanillin alcohol and using a combination of an enzyme cascade system and catalysts. Furthermore, the method also relates to synthesis of capsaicinoids derivatives starting from vanillin alcohol derivatives and using a combination of an enzyme cascade system and catalysts.
Type:
Grant
Filed:
March 27, 2015
Date of Patent:
November 9, 2021
Assignee:
XP Chemistries AB
Inventors:
Armando Córdova, Per Berglund, Mattias Anderson, Samson Afewerki