Patents Assigned to XPRESS BIOLOGICS
  • METHOD FOR PURIFYING A PROTEIN OF INTEREST
    Publication number: 20240228529
    Abstract: A method is for purifying a biomolecule (protein, DNA) of interest from a culture of Gram-negative bacteria uses polyoxyethylene isooctylcyclohexyl ether to remove endotoxins. Polyoxyethylene isooctylcyclohexyl ether is used to remove endotoxins and a solution having a pH between 8.0 and 9.0 and a concentration of salts from 2.5M to 3M in chromatography is used for specific leaching of bacterial contaminants.
    Type: Application
    Filed: February 28, 2022
    Publication date: July 11, 2024
    Applicant: XPRESS BIOLOGICS
    Inventors: Marc DAUKANDT, Philippe LEDENT, Christian RODRIQUEZ
  • METHOD FOR PURIFYING A PROTEIN OF INTEREST
    Publication number: 20240132537
    Abstract: A method is for purifying a biomolecule (protein, DNA) of interest from a culture of Gram-negative bacteria uses polyoxyethylene isooctylcyclohexyl ether to remove endotoxins. Polyoxyethylene isooctylcyclohexyl ether is used to remove endotoxins and a solution having a pH between 8.0 and 9.0 and a concentration of salts from 2.5M to 3M in chromatography is used for specific leaching of bacterial contaminants.
    Type: Application
    Filed: February 28, 2022
    Publication date: April 25, 2024
    Applicant: XPRESS BIOLOGICS
    Inventors: Marc DAUKANDT, Philippe LEDENT, Christian RODRIQUEZ