Patents Assigned to XSPRAY PHARMA AB
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Patent number: 12576071Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: December 2, 2024Date of Patent: March 17, 2026Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20250375449Abstract: Disclosed herein is a composition comprising: an amorphous solid dispersion (ASD) comprising nilotinib and at least one polymeric stabilizing and matrix-forming component; and at least one solid organic acid in admixture with the ASD, and uses thereof in the treatment of proliferative disorder.Type: ApplicationFiled: August 25, 2025Publication date: December 11, 2025Applicant: XSPRAY PHARMA ABInventors: Andreas FISCHER, Thomas ANDERSSON
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Patent number: 12419892Abstract: Disclosed herein is a composition comprising: an amorphous solid dispersion (ASD) comprising nilotinib and at least one polymeric stabilizing and matrix-forming component; and at least one solid organic acid in admixture with the ASD, and uses thereof in the treatment of proliferative disorder.Type: GrantFiled: November 8, 2024Date of Patent: September 23, 2025Assignee: XSPRAY PHARMA ABInventors: Andreas Fischer, Thomas Andersson
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Publication number: 20250090511Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: ApplicationFiled: December 2, 2024Publication date: March 20, 2025Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Mustafa DEMIRBÜKER, Gérald JESSON, Martin MALMSTEN, Helene DÉRAND
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Publication number: 20240398769Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: ApplicationFiled: August 15, 2024Publication date: December 5, 2024Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Mustafa DEMIRBÜKER, Gérald JESSON, Martin MALMSTEN, Helene DÉRAND
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Patent number: 12144804Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: July 22, 2024Date of Patent: November 19, 2024Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20240374577Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: ApplicationFiled: July 22, 2024Publication date: November 14, 2024Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Mustafa DEMIRBÜKER, Gérald JESSON, Martin MALMSTEN, Helene DÉRAND
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Patent number: 12076314Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: January 12, 2024Date of Patent: September 3, 2024Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20240189290Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: ApplicationFiled: January 12, 2024Publication date: June 13, 2024Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Mustafa DEMIRBÜKER, Gérald JESSON, Martin MALMSTEN, Helene DÉRAND
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Patent number: 11963951Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: December 16, 2021Date of Patent: April 23, 2024Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20240024248Abstract: The present disclosure relates to the field of pharmaceutical compositions. Furthermore, the present invention relates to an immediate release pharmaceutical composition in the form of a non-effervescent tablet composition comprising dasatinib and a gas generating agent.Type: ApplicationFiled: July 27, 2023Publication date: January 25, 2024Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Thomas MEIJER, Victor SÖDERBERG
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Patent number: 11833249Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.Type: GrantFiled: May 6, 2022Date of Patent: December 5, 2023Assignee: XSPRAY PHARMA ABInventors: Per Andersson, Thomas Meijer, Victor Söderberg
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Publication number: 20230121325Abstract: The present disclosure relates to the field of pharmaceutical compositions. Furthermore, the present invention relates to an immediate release pharmaceutical composition in the form of a non-effervescent tablet composition comprising dasatinib and a gas generating agent.Type: ApplicationFiled: December 12, 2022Publication date: April 20, 2023Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Thomas MEIJER, Victor SÖDERBERG
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Patent number: 11529351Abstract: The present disclosure relates to the field of pharmaceutical compositions. Furthermore, the present invention relates to an immediate release pharmaceutical composition in the form of a non-effervescent tablet composition comprising dasatinib and a gas generating agent.Type: GrantFiled: January 21, 2022Date of Patent: December 20, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Thomas Meijer, Victor Söderberg
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Patent number: 11517562Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: June 1, 2022Date of Patent: December 6, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20220296575Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: ApplicationFiled: June 1, 2022Publication date: September 22, 2022Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Mustafa DEMIRBÜKER, Gérald JESSON, Martin MALMSTEN, Helene DÉRAND
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Patent number: 11426391Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: February 14, 2022Date of Patent: August 30, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand
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Publication number: 20220257519Abstract: The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.Type: ApplicationFiled: May 6, 2022Publication date: August 18, 2022Applicant: XSPRAY PHARMA ABInventors: Per ANDERSSON, Thomas MEIJER, Victor SÖDERBERG
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Publication number: 20220233532Abstract: The present disclosure relates to the field of pharmaceutical compositions. Furthermore, the present invention relates to an immediate release pharmaceutical composition in the form of a non-effervescent tablet composition comprising dasatinib and a gas generating agent.Type: ApplicationFiled: January 21, 2022Publication date: July 28, 2022Applicant: XSPRAY PHARMA ABInventors: Magnus BRISANDER, Thomas MEIJER, Victor SÖDERBERG
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Patent number: 11376243Abstract: The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.Type: GrantFiled: February 14, 2022Date of Patent: July 5, 2022Assignee: XSPRAY PHARMA ABInventors: Magnus Brisander, Mustafa Demirbüker, Gérald Jesson, Martin Malmsten, Helene Dérand