Patents Assigned to Xtent, Inc.
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Patent number: 7892273Abstract: Apparatus and methods for delivering prosthetic segments to a body lumen, utilize a device having an elongated flexible member including proximal and distal ends, a plurality of prosthetic segments releasably arranged axially along the elongated flexible member near the distal end and an outer sheath slidably disposed over at least a portion of the prosthetic segments. The apparatus further includes a separator disposed on the outer sheath and adapted to engage the prosthetic segments. The separator is also adapted to be retracted proximally over the prosthetic segments and advanced distally to separate a proximal group of the prosthetic segments from a distal group of the prosthetic segments which are to be deployed in the body lumen.Type: GrantFiled: September 1, 2006Date of Patent: February 22, 2011Assignee: Xtent, Inc.Inventors: Robert George, David W. Snow, Harold F. Carrison, Pablo Acosta
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Publication number: 20110022148Abstract: An implant comprises a structure that may be implanted into tissue and that has a first material property at normal body temperature. The first material property is variable at elevated temperatures above normal body temperature. The implant also has a plurality of particles dispersed in the structure that are adapted to convert incident radiation into heat energy when irradiated with electromagnetic radiation. The particles are in thermal contact with the structure such that exposure of the particles to incident radiation raises the temperature of the structure thereby changing the first material property relative to the first material property at normal body temperature.Type: ApplicationFiled: September 28, 2010Publication date: January 27, 2011Applicant: Xtent, Inc.Inventors: Patrick H. Ruane, Cameron L. Wilson
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Publication number: 20100004729Abstract: Blood vessels and other body lumens are stented using multiple, discreet stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having both a pusher rod for advancing the stents relative to a sheath and a reciprocatable delivery catheter for implanting the stents.Type: ApplicationFiled: June 10, 2009Publication date: January 7, 2010Applicant: Xtent, Inc.Inventors: Sunmi Chew, Bernard Andreas, Hanson S. Gifford, III, Ron French, Mark E. Deem, Allan Will
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Publication number: 20090299461Abstract: A catheter configured to carry one or more stents and having an inflatable balloon for expanding a stent surrounding the balloon. The catheter is characterized in having a positioner for moving the one or more stents relative to the balloon from a first position in which the stent does not surround the balloon to a second position in which the stent surrounds the balloon. Also disclosed is a method for deploying a stent at a desired location in the vascular system.Type: ApplicationFiled: July 15, 2009Publication date: December 3, 2009Applicant: XTENT, INC.Inventor: Israel Chermoni
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Publication number: 20090299458Abstract: A catheter configured to carry one or more stents and having an inflatable balloon for expanding a stent surrounding the balloon. The catheter is characterized in having a positioner for moving the one or more stents relative to the balloon torn a first position in which the stent does not surround the balloon to a second position in which the stent surrounds the balloon. Also disclosed is a method for deploying a stent at a desired location in the vascular system.Type: ApplicationFiled: July 15, 2009Publication date: December 3, 2009Applicant: XTENT, INC.Inventor: Israel S. Chermoni
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Publication number: 20090276031Abstract: Apparatus for delivering stents to body lumens include one or more tubular prostheses carried at the distal end of a catheter shaft, a sheath slidably disposed over the prostheses, and a guidewire tube extending from within the sheath to the exterior of the sheath through an exit port in a sidewall thereof A guidewire extends slidably through the guidewire tube. The sheath can be moved relative to the catheter shaft and the guidewire tube to expose the prostheses for deployment. Methods of delivering stents are also provided.Type: ApplicationFiled: June 12, 2009Publication date: November 5, 2009Applicant: XTENT, Inc.Inventor: Stephen KAO
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Publication number: 20090264979Abstract: Blood vessels and other body lumens are stented using stent structures comprising a plurality of radially expansible rings where at least some of the rings comprise axially extending elements which interleave with axially extending elements on adjacent unconnected rings. The ring structures may be open cell structures or closed cell structures, and the axially extending elements will typically be formed as part of the open cell or closed cell structure.Type: ApplicationFiled: June 26, 2009Publication date: October 22, 2009Applicant: Xtent, Inc.Inventors: Stephen Kao, Bernard Andreas, Hanson S. Gifford, III, Mark E. Deem, David W. Snow, Jeffry J. Grainger
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Publication number: 20090248137Abstract: An expandable stent comprising a tubular body made up of a plurality of separated tubular elements (1) arranged along a common longitudinal axis. Each tubular element (1) comprises a plurality of rhombic-shaped closed cell elements (2) joined by circumferentially extending linking members (3). The closed cell elements (2) are expandable to allow the tubular elements, and hence the stent itself, to expand. In the direction of the longitudinal axis of the stent, the extremities of each of the closed cell elements has an enlarged loop (30) with waisted portions (33) which allow the tubular elements to interlock to create a stable structure, at least when in the unexpanded condition.Type: ApplicationFiled: June 10, 2009Publication date: October 1, 2009Applicant: Xtent, Inc.Inventors: Erik Andersen, Ning Wen
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Publication number: 20090234428Abstract: Prosthesis delivery devices and methods are provided that enable precise control of prosthesis position during deployment. The prosthesis delivery devices may carry multiple prostheses and include deployment mechanisms for delivery of a selectable number of prostheses. Control mechanisms are provided in the prosthesis delivery devices that control either or both of the axial and rotational positions of the prostheses during deployment. This enables the deployment of multiple prostheses at a target site with precision and predictability, eliminating excessive spacing or overlap between prostheses. In particular embodiments, the prostheses of the invention are deployed in stenotic lesions in coronary or peripheral arteries, or in other vascular locations.Type: ApplicationFiled: May 22, 2009Publication date: September 17, 2009Applicant: Xtent, Inc.Inventors: David W. Snow, Joseph Karratt, Jeffry J. Grainger, Denise Demarais
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Publication number: 20090228088Abstract: A tubular prosthesis has a plurality of tubular rings that are radially expandable from a contracted configuration to an expanded configuration. Each ring comprises a plurality of axially oriented struts that are interconnected so as to form a circumferential series of at least one high peak and at least one low peak. The high and low peaks have apices that are oriented in the same axial direction. The apices of the high and low peaks are also oriented in the same direction and the apices of the high peaks are axially offset from the apices of the low peaks. A bridge member couples a pair of adjacent tubular rings together. The bridge member has a first end connected to a first low peak in a first tubular ring and a second end connected to either a high or low peak in an adjacent tubular ring.Type: ApplicationFiled: March 6, 2008Publication date: September 10, 2009Applicant: XTENT, INC.Inventors: David Lowe, Craig Bonsignore, David W. Snow, Timothy Robinson, Joshua P. Wiesman, Dawn Henderson, Nathan Maier
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Patent number: 7553324Abstract: Stent delivery devices and methods include multiple stents or stent segments mounted at fixed positions on an expandable member of the stent delivery catheter. One or more of the fixed-position stents may be selectively deployed in a body lumen such as a blood vessel by positioning one or more sheaths to constrain some stents while exposing other for deployment. Some embodiments include two axially movable sheaths for serially deploying stents while containing a portion of the expandable balloon from which stents have been deployed. Other embodiments include inner and outer balloon shafts to allow the balloon to be retracted into the delivery catheter as stents are deployed. Devices and methods of the invention provide enhanced serial deployment of multiple stents or stent segments while reducing the risk of damage to an expandable deployment member.Type: GrantFiled: October 14, 2003Date of Patent: June 30, 2009Assignee: Xtent, Inc.Inventors: Bernard Andreas, Jeffry J. Grainger
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Publication number: 20090149863Abstract: Stent delivery devices and methods include multiple stents or stent segments mounted at fixed positions on an expandable member of the stent delivery catheter. One or more of the fixed-position stents may be selectively deployed in a body lumen such as a blood vessel by positioning one or more sheaths to constrain some stents while exposing others for deployment. Some embodiments include two axially movable sheaths for serially deploying stents while containing a portion of the expandable balloon from which stents have been deployed. Other embodiments include inner and outer balloon shafts to allow the balloon to be retracted into the delivery catheter as stents are deployed. Devices and methods of the invention provide enhanced serial deployment of multiple stents or stent segments while reducing the risk of damage to an expandable deployment member.Type: ApplicationFiled: February 18, 2009Publication date: June 11, 2009Applicant: Xtent, Inc.Inventors: Bernard Andreas, Jeffry J. Grainger
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Publication number: 20090105686Abstract: A drug or agent coated balloon having a length which is adjustable in vivo is described herein. The balloon is configured to be coated or coatable with one or more drugs where the coating may be applied prior to advancement into a patient body or prior to balloon expansion within the patient body. The length of the expandable portion of the balloon is adjustable to approximate a length of the tissue region to be treated. Moreover, the drug-coated balloon may be used alone or it may be utilized to deploy luminal prostheses having one or more linked or otherwise coupled segments.Type: ApplicationFiled: June 29, 2007Publication date: April 23, 2009Applicant: Xtent, Inc.Inventors: David W. Snow, Patrick H. Ruane
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Publication number: 20090088832Abstract: Blood vessels and other body lumens are stented using multiple, discrete stent structures, or continuous coiled or mesh stent structures. Stent structures may be a balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sites. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having a deployment mechanism for deploying one or more stents of selectable length into the vessel.Type: ApplicationFiled: November 12, 2007Publication date: April 2, 2009Applicant: XTENT, INC.Inventors: Sunmi Chew, Bernard Andreas, Hanson S. Gifford, III, Ron French, Mark E. Deem, Allan Will
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Publication number: 20090076584Abstract: A catheter for delivering a prosthesis to a target treatment site comprises an inner shaft and an expansion member coupled to the inner shaft. A plurality of radially expandable prosthetic segments are positionable over the expansion member and they are releasably interlocked with one another while unexpanded. Adjacent pairs of prosthetic segments may decouple from one another upon radial expansion of the distal prosthetic segment in the adjacent pair while the proximal segment in the pair remains at least partially unexpanded. The catheter also includes an outer sheath that is axially movable and positionable at least partially over the prosthetic segments to constrain expansion of a selectable number of segments. A segment mover is coupled to at least one of the prosthetic segments and is axially movable so as to retract one or more of the segments when the one or more prosthetic segments are unexpanded.Type: ApplicationFiled: September 19, 2007Publication date: March 19, 2009Applicant: Xtent, Inc.Inventors: Bryan Mao, Pablo Acosta
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Publication number: 20080269865Abstract: Apparatus and methods for delivering prosthetic segments to a body lumen include an elongated flexible member having both proximal and distal ends along with a plurality of prosthetic segments releasably arranged axially along the elongated flexible member near the distal end. Additionally, the apparatus has a sheath slidably disposed over at least a portion of the prosthetic segments and an outer shaft slidably disposed over at least a portion of the sheath. A separator is disposed on the outer shaft and is biased into engagement with at least one prosthetic segment so that the outer shaft may be retracted to separate a proximal group of prosthetic segments from a distal group of prosthetic segments which are to be deployed into the body lumen. The sheath is positionable between the separator and the prosthetic segments to selectively disengage the separator from the prosthetic segments.Type: ApplicationFiled: August 7, 2006Publication date: October 30, 2008Applicant: XTENT, INC.Inventors: David W. Snow, Robert George
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Publication number: 20080234795Abstract: A catheter for delivering a prosthesis to a treatment site in a body lumen comprises an elongate flexible member and a sheath slidably disposed thereover. A plurality of self-expanding tubular prostheses are carried in axially spaced apart locations along the elongate member, within the sheath. The prostheses may be selectively interlocked with one another and are constrained by the sheath in a radially contracted configuration. The prostheses are separately releasable from the sheath when the sheath is retracted relative to the elongate member. The catheter also has a pusher member slidably disposed along the elongate member within the sheath. The pusher is adapted to move past the prostheses in a first direction without displacing the prostheses, while in a second direction the pusher engages a selected prosthesis so as to move the prosthesis with the pusher to interlock the selected prosthesis with a second prosthesis.Type: ApplicationFiled: March 22, 2007Publication date: September 25, 2008Applicant: XTENT, Inc.Inventors: David W. Snow, Denise Demarais, Stuart Lin
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Publication number: 20080234798Abstract: Blood vessels and other body lumens are stented using multiple, discreet stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having both a pusher rod for advancing the stents relative to a sheath and a reciprocatable delivery catheter for implanting the stents.Type: ApplicationFiled: May 27, 2008Publication date: September 25, 2008Applicant: XTENT, INC.Inventors: Sunmi Chew, Bernard Andreas, Hanson S. Gifford, Ron French, Mark E. Deem, Allan Will
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Publication number: 20080234799Abstract: A stent delivery system for delivering a plurality of stent segments to at least one treatment site includes a catheter shaft having a proximal end and a distal end, a plurality of expandable members arranged axially along the catheter shaft near the distal end, a plurality of stent segments, and a selecting mechanism adapted for selecting one or more expandable members for expansion. Each expandable member is expandable independently of at least one other expandable member, and each expandable member has at least one stent segment positioned on it. One or more of the expandable members may be selectively expanded to deploy the one or more stent segments positioned thereon at the treatment site.Type: ApplicationFiled: June 5, 2008Publication date: September 25, 2008Applicant: XTENT, INC.Inventors: Pablo Acosta, David Sanderson
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Publication number: 20080208311Abstract: Blood vessels and other body lumens are stented using stent structures comprising a plurality of radially expansible rings where at least some of the rings comprise axially extending elements which interleave with axially extending elements on adjacent unconnected rings. The ring structures may be open cell structures or closed cell structures, and the axially extending elements will typically be formed as part of the open cell or closed cell structure.Type: ApplicationFiled: April 25, 2008Publication date: August 28, 2008Applicant: XTENT, INC.Inventors: Stephen Kao, Bernard Andreas, Hanson S. Gifford, Mark E. Deem, David W. Snow, Jeffry J. Grainger