Patents Assigned to XW LABORATORIES INC.
  • Compounds as neuronal histamine receptor-3 antagonists and uses thereof
    Patent number: 10968202
    Abstract: The present invention relates compounds of Formula (A) as H3R antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of Histamine 3 Receptor (H3R) functions. The present invention also relates to the uses of the compounds or pharmaceutical compositions in treating or preventing certain disorders and diseases which relate to H3R functions in humans.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: April 6, 2021
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Yi Feng, Wai-Si Eng
  • Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
    Patent number: 10941107
    Abstract: Provided are prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: March 9, 2021
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Xuan Zhang
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20210032199
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: October 12, 2020
    Publication date: February 4, 2021
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, HAO-WEI SHIH, WAI-SI ENG
  • Reactive oxygen species scavengers and use for treating diseases
    Patent number: 10889572
    Abstract: A compound of Formula (I), pharmaceutically acceptable salts thereof, and individual enantiomers or diastereomers thereof. Compositions and methods useful for treatment or suppression of diseases, developmental delays and symptoms related to oxidative stress.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: January 12, 2021
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • Bicyclic heteroaryl derivatives and preparation and uses thereof
    Patent number: 10882832
    Abstract: The present invention relates compounds of Formula (A), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate transmission. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing certain neurological and psychiatric disorders and diseases as well as cancer in humans.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: January 5, 2021
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Wei Zhou
  • Preparation and uses of reactive oxygen species scavenger derivatives
    Patent number: 10858394
    Abstract: Compounds of Formula (I)a or (I)b: including certain quinone derivatives, and the corresponding pharmaceutical compositions, which may serve to modulate ferroptosis in a subject. Also disclosed herein are the preparations of these compounds and pharmaceutical compositions and their potential uses in the manufacture of a medicament in reducing reactive oxygen species (ROS) in a cell and for preventing, treating, ameliorating certain related disorder or a disease.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: December 8, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Zude Qi, Dezheng Ning, Xianbo Liu
  • PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF
    Publication number: 20200369598
    Abstract: Provided are prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Application
    Filed: August 7, 2020
    Publication date: November 26, 2020
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, XUAN ZHANG
  • PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF
    Publication number: 20200369599
    Abstract: Provided are prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Application
    Filed: August 7, 2020
    Publication date: November 26, 2020
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, XUAN ZHANG
  • Ketamine derivatives and compositions thereof
    Patent number: 10836714
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: November 17, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-Si Eng
  • Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
    Patent number: 10774031
    Abstract: The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: September 15, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Xuan Zhang
  • Compounds as neuronal histamine receptor-3 antagonists and uses thereof
    Patent number: 10730853
    Abstract: The present invention relates compounds of Formula (A) as H3R antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of Histamine 3 Receptor (H3R) functions. The present invention also relates to the uses of the compounds or pharmaceutical compositions in treating or preventing certain disorders and diseases which relate to H3R functions in humans.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: August 4, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Yi Feng, Wai-Si Eng
  • KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF
    Publication number: 20200231540
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Application
    Filed: April 2, 2020
    Publication date: July 23, 2020
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, HAO-WEI SHIH, WAI-SI ENG
  • PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF
    Publication number: 20200223783
    Abstract: The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Application
    Filed: March 26, 2020
    Publication date: July 16, 2020
    Applicant: XW LABORATORIES INC.
    Inventors: JIA-NING XIANG, XUESONG XU, XUAN ZHANG
  • Ketamine derivatives and compositions thereof
    Patent number: 10683262
    Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: June 16, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-si Eng
  • Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
    Patent number: 10640451
    Abstract: The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: May 5, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Xuan Zhang
  • Bicyclic heteroaryl derivatives and preparation and uses thereof
    Patent number: 10640476
    Abstract: The present invention relates compounds of Formula (A), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate transmission. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing certain neurological and psychiatric disorders and diseases as well as cancer in humans.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: May 5, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Wei Zhou
  • Compounds as neuronal histamine receptor-3 antagonists and uses thereof
    Patent number: 10618886
    Abstract: The present invention relates compounds of Formula (A) as H3R antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of Histamine 3 Receptor (H3R) functions. The present invention also relates to the uses of the compounds or pharmaceutical compositions in treating or preventing certain disorders and diseases which relate to H3R functions in humans.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: April 14, 2020
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Yi Feng, Wai-Si Eng
  • Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
    Patent number: 10501401
    Abstract: The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Grant
    Filed: February 13, 2019
    Date of Patent: December 10, 2019
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Xuan Zhang
  • Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
    Patent number: 10457627
    Abstract: The present disclosure discloses prodrugs of gamma-hydroxybutyric acid as well as compositions and uses thereof.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: October 29, 2019
    Assignee: XW LABORATORIES INC.
    Inventors: Jia-Ning Xiang, Xuesong Xu, Xuan Zhang