Abstract: A method of analyzing thrombotic activity of blood samples that includes providing a capillary tube between a vessel containing a sample of blood and a collection reservoir, applying pressure to the blood to draw it from the vessel through the capillary tube and into the reservoir for a predetermined period of time, and measuring the blood collected in the reservoir within the predetermined time period as an indication of the platelet activity of the blood sample. By following these simple steps it is possible to produce measurements which are meaningful and physiologically relevant.
Abstract: A disposable cartridge for measuring the physical properties of blood is disclosed. A waste compartment supports a platform having first and second syringe fittings. First and second syringes containing blood samples to be measured are positioned within the fittings. At least one testing station is located on the platform for subjecting blood flowing from one of the syringes to a test station, and the testing station is connected at a second end to the waste compartment. Tests on blood running through each of the blood channels may be conducted by inducing various platelet activation conditions, such as piercing a channel, or putting a platelet activating substance within a test channel. The cartridge interfaces with a test stand which will measure pressure changes within each of the test channels.
Type:
Grant
Filed:
December 7, 1992
Date of Patent:
May 31, 1994
Assignee:
XYLUM Corporation
Inventors:
Joseph W. Blake, Robert Cousineau, Mark Rosen, William Watson
Abstract: A disposable blood holding cassette for haemostatic measurements. A single unit is provided having a blood sample container with three separate pressurized blood sample reservoirs. A waste blood collection reservoir is connected to the blood sample container, and connected thereto via first, second and third blood sample tubes. A punching station is provided to accurately punch first and second of the blood sample tubes, simulating haemostasis function in vitro. Measurements may be made of the haemostatic and thrombolytic function of recently sampled blood. The entire device is disposable, isolating any contaminated blood from clinical personnel.
Type:
Grant
Filed:
August 18, 1989
Date of Patent:
September 10, 1991
Assignee:
Xylum Corporation
Inventors:
Thomas E. Sloane, Jr., Joseph W. Blake, III
Abstract: A disposable cartridge for measuring the physical properties of blood is disclosed. A waste compartment supports a platform having first and second syringe fittings. First and second syringes containing blood samples to be measured are positioned within the fittings. At least one testing station is located on the platform for subjecting blood flowing from one of the syringes to a test station, and the testing station is connected at a second end to the waste compartment. Tests on blood running through each of the blood channels may be conducted by inducing various platelet activation conditions, such as piercing a channel, or putting a platelet activating substance within a test channel. The cartridge interfaces with a test stand which will measure pressure changes within each of the test channels.
Type:
Grant
Filed:
May 30, 1996
Date of Patent:
January 19, 1999
Assignee:
XYLUM Corporation
Inventors:
Joseph Blake, Robert P. Cousineau, Mark I. Rosen, William C. Watson