Patents Assigned to Yamada Apiculture Center, Inc.
  • Carboxylic acid and antidepressant composition containing the same as active ingredient
    Patent number: 8119839
    Abstract: The present invention provides a novel compound and antidepressant composition that can be effectively used for improving depressed mood and depressed state, particularly for depressed mood and depressed state in menopausal women. The compound of the present invention is represented by the following formula (1): wherein R1 and R2 are identical or different and represent a hydrogen atom, a hydroxyl group or an acetyloxy group, and n is an integer of 2 to 7, or a pharmaceutically acceptable salt or ester thereof. This compound is used as an active ingredient in the antidepressant composition. Examples of the compound of the invention include (2E)-9,10-dihydroxy-2-decenoic acid, (2Z)-9,10-dihydroxy-2-decenoic acid, (2E)-9-hydroxy-2-decenoic acid, and (2E)-7-acetoxy-2-heptenoic acid.
    Type: Grant
    Filed: July 19, 2008
    Date of Patent: February 21, 2012
    Assignee: Yamada Apiculture Center, Inc.
    Inventors: Hiroyuki Yoshimura, Kiyoshi Okihara, Satoshi Kawatake, Hiroko Tani, Tomoki Tatefuji, Ken Hashimoto, Hiromasa Tanaka, Akinori Inoue, Miyako Yanagihara
  • Novel Carboxylic Acid and Antidepressant Composition Containing the Same as Active Ingredient
    Publication number: 20100184860
    Abstract: The present invention provides a novel compound and antidepressant composition that can be effectively used for improving depressed mood and depressed state, particularly for depressed mood and depressed state in menopausal women. The compound of the present invention is represented by the following formula (1): wherein R1 and R2 are identical or different and represent a hydrogen atom, a hydroxyl group or an acetyloxy group, and n is an integer of 2 to 7, or a pharmaceutically acceptable salt or ester thereof. This compound is used as an active ingredient in the antidepressant composition. Examples of the compound of the invention include (2E)-9,10-dihydroxy-2-decenoic acid, (2Z)-9,10-dihydroxy-2-decenoic acid, (2E)-9-hydroxy-2-decenoic acid, and (2E)-7-acetoxy-2-heptenoic acid.
    Type: Application
    Filed: July 19, 2008
    Publication date: July 22, 2010
    Applicant: YAMADA APICULTURE CENTER, INC.
    Inventors: Hiroyuki Yoshimura, Kiyoshi Okihara, Satoshi Kawatake, Hiroko Tani, Tomoki Tatefuji, Ken Hashimoto, Hiromasa Tanaka, Akinori Inoue, Miyako Yanagihara