Abstract: A novel packing material suitable for high pressure liquid chromatography comprising the chemically bonded, crosslinked reaction product of porous inorganic particles, with an organic silane compound having epoxy groups on the surface of the particles, and then with polyvinyl alcohol, in which the hydroxyl groups of the polyvinyl alcohol and the epoxy groups on the silane moieties react to form ether bonds, which cover almost or almost completely the residual silica hydroxyl groups on the surface of the support.
Type:
Grant
Filed:
February 10, 1988
Date of Patent:
May 9, 1989
Assignee:
Yamamura Chemical Laboratories, Co., Ltd.