Patents Assigned to Yamazen Corporation
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Patent number: 11204345Abstract: To provide a preparative thin layer chromatography method capable of acquiring a target spot efficiently using a simple and convenient method without the possibility of decomposition of a component in a spot. The preparative thin layer chromatography method is a preparative method for dispensing a spot from a thin layer chromatography plate and includes a process 1 that forms a groove by removing the carrier at the circumferential edge of a spot to be dispensed, a process 2 that inserts a nozzle having a packing part at the tip thereof into the groove formed in the process 1, a process 3 that discharges a solvent through the nozzle, and a process 4 that sucks the solvent in which a spot component has been dissolved.Type: GrantFiled: January 17, 2019Date of Patent: December 21, 2021Assignee: YAMAZEN CORPORATIONInventor: Kihachiro Okura
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Patent number: 11002714Abstract: Provided that elapsed time from the start of the flow-in of an eluent into a column is t0 and the mobility Rfc(t/t0) of a component c in a sample is represented by a function of elapsed time t from the start of the flow-in of a sample into the column, elution time trc from the flow-in of the sample into the column to the flow-out of the component c from the column is calculated by using Equation (1). In doing so, the mobility Rfc(t/t0) in Equation (1) is represented by Equation (2).Type: GrantFiled: November 30, 2015Date of Patent: May 11, 2021Assignee: Yamazen CorporationInventor: Kihachiro Okura
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Patent number: 10648954Abstract: An object of the present disclosure is to find a method in which a result of liquid chromatography can be predicted with high accuracy for a wide range of a mixing ratio of solvents by utilizing a result of thin-layer chromatography. A liquid chromatography method for separating a mixture of two or more kinds of compounds, comprising the following steps: (1) performing thin-layer chromatography or column chromatography in a mixed solvent of two or more kinds of solvents having a different mixing ratio from each other or a single solvent; (2) creating a relational expression between a mixing ratio and an elution degree of a solvent for each compound in a sample based on a result of the step (1); and (3) determining an optimum condition based on the relational expression, and performing liquid chromatography.Type: GrantFiled: January 10, 2017Date of Patent: May 12, 2020Assignee: YAMAZEN CORPORATIONInventor: Kihachiro Okura
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Patent number: 10416135Abstract: A preparative liquid chromatographic apparatus comprising a column for separating components in a sample; a dispensing unit for dispensing an eluate from the column; a detector for the eluate; an analysis unit for the eluate; a display unit for displaying an analysis result a data storage unit; and an arithmetic control unit for controlling the display unit and the data storage unit. The analysis unit has at least one qualitative analysis unit for continuously and qualitatively analyzing the eluate. The display unit simultaneously displays a chromatogram acquired by the detector and the acquisition position of the dispensing unit and displays a correspondence relationship between each fraction and the chromatogram, and wherein by using the correspondence relationship between each fraction and the chromatogram shown in the display unit, the qualitative analysis data selected from the data storage unit is displayed on the display unit using the arithmetic control unit.Type: GrantFiled: January 11, 2017Date of Patent: September 17, 2019Assignee: YAMAZEN CORPORATIONInventor: Kihachiro Okura
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Publication number: 20160077065Abstract: Provided that elapsed time from the start of the flow-in of an eluent into a column is t0 and the mobility Rfc(t/t0) of a component c in a sample is represented by a function of elapsed time t from the start of the flow-in of a sample into the column, elution time trc from the flow-in of the sample into the column to the flow-out of the component c from the column is calculated by using Equation (1). In doing so, the mobility Rfc(t/t0) in Equation (1) is represented by Equation (2).Type: ApplicationFiled: November 30, 2015Publication date: March 17, 2016Applicant: Yamazen CorporationInventor: Kihachiro Okura
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Publication number: 20130032520Abstract: Provided that elapsed time from the start of the flow-in of an eluent into a column is t0 and the mobility Rfc(t/t0) of a component c in a sample is represented by a function of elapsed time t from the start of the flow-in of a sample into the column, elution time trc from the flow-in of the sample into the column to the flow-out of the component c from the column is calculated by using Equation (1). In doing so, the mobility Rfc(t/t0) in Equation (1) is represented by Equation (2).Type: ApplicationFiled: August 1, 2012Publication date: February 7, 2013Applicant: Yamazen CorporationInventor: Kihachiro Okura
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Patent number: 7169308Abstract: A liquid chromatograph control apparatus (1) includes a measured value storage (25a) that stores a measured retardation factor (Rf) value of a sample (3), which is obtained when components of the sample are separated on thin layer chromatography using eluent (4) containing a plurality of ingredients at a specified mixture ratio, in association with the specified mixture ratio, a rate-of-change-in-Rf-value storage (25b) that stores a rate of change in the Rf value of the sample (3) with respect to variation in mixture ratio of ingredients of eluent (10), a mixture ratio calculator (22a) that determines a mixture ratio of the eluent (10) at which a specified retardation factor value (RfO) of the sample is obtained, based on the measured Rf value corresponding to the specified mixture ratio stored in the measured value storage (25a) and on the rate of change in the Rf value stored in the rate-of-change-in-Rf-value storage (25b), and a mixture ratio controller (22b) that outputs a control signal to control the miType: GrantFiled: February 14, 2003Date of Patent: January 30, 2007Assignee: Yamazen CorporationInventor: Kihachiro Ohkura
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Publication number: 20060231471Abstract: A liquid chromatograph control apparatus (1) includes a measured value storage (25a) that stores a measured retardation factor (Rf) value of a sample (3), which is obtained when components of the sample are separated on thin layer chromatography using eluent (4) containing a plurality of ingredients at a specified mixture ratio, in association with the specified mixture ratio, a rate-of-change-in-Rf-value storage (25b) that stores a rate of change in the Rf value of the sample (3) with respect to variation in mixture ratio of ingredients of eluent (10), a mixture ratio calculator (22a) that determines a mixture ratio of the eluent (10) at which a specified retardation factor value (RfO) of the sample is obtained, based on the measured Rf value corresponding to the specified mixture ratio stored in the measured value storage (25a) and on the rate of change in the Rf value stored in the rate-of-change-in-Rf-value storage (25b), and a mixture ratio controller (22b) that outputs a control signal to control the miType: ApplicationFiled: February 14, 2003Publication date: October 19, 2006Applicant: Yamazen CorporationInventor: Kihachiro Ohkura
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Patent number: 6415670Abstract: An injection apparatus of the present invention includes a first switching valve RV1 which is selectively connected to any of a plurality of injectors 21-30 at one end sides thereof; a second switching valve RV2 which is selectively connected to any of the plurality of injectors at the other end sides thereof; a third switching valve RV4 which is connected to the second switching valve and is selectively connected to any of a plurality of columns 31-40 at one end sides thereof; and a fourth switching valve RV5 which is selectively connected to any of the plurality of columns at the other end sides thereof A sequential switching of these four switching valves can permit the sample liquids in the injectors 21-30 to be delivered in sequence into any selected column 31-40, and as such can allow the sample liquids packed in the plurality of injectors to be efficiently dispensed or analyzed by a chromatograph.Type: GrantFiled: March 27, 2000Date of Patent: July 9, 2002Assignee: Yamazen CorporationInventors: Kihachiro Ohkura, Shigeo Mukai, Kunihiko Fujii