Patents Assigned to YANGZHOU UNIVERSITY
  • Patent number: 12285013
    Abstract: The present invention relates to a processing method for increasing seed production rate of seed fruits of Cucumis sativus L., comprising the following steps: (1) preparing a plant growth regulator according to a formula proportion; (2) selecting seed fruits of Cucumis sativus L. growing naturally in a greenhouse and reaching a pollination stage, and dipping female flowers thereof with the plant growth regulator prepared in step (1) before pollination; (3) picking male flowers for pollination after the female flowers are completely dry; (4) dipping the pollinated female flowers again; (5) conducting field routine cultivation management. The present invention uses a DNA methyltransferase inhibitor “5-azacytidine” (C8H12N4O5) to treat the seed fruits of Cucumis sativus L. by soaking and dipping, wherein 5-azacytidine increases seed production efficiency by reducing fruit length of the seed fruits, reducing fruit weight and reducing nutrient loss for fruit growth.
    Type: Grant
    Filed: August 27, 2024
    Date of Patent: April 29, 2025
    Assignee: Yangzhou University
    Inventors: Xiaodong Yang, Yizhuo Deng, Lili Zhang, Lei Qiu, Jieni Gu, Xuehao Chen
  • Publication number: 20250110125
    Abstract: A hybridoma cell line secreting an ActA monoclonal antibody and a use thereof. The hybridoma cell line was deposited on Jul. 8, 2021, at the China Center for Type Culture Collection (CCTCC) with the depository accession number of CCTCC NO: C2021174. The present invention also discloses the ActA monoclonal antibody secreted by this hybridoma cell line or its progeny cell line, a detection kit containing this ActA monoclonal antibody, immunomagnetic beads, the preparation method and use of immunomagnetic beads, and competitive ELISA and indirect ELISA detection methods. The ActA monoclonal antibody of the present invention has the advantages of high titer, good specificity, and strong affinity with the natural antigen. The Listeria competitive ELISA detection kit and immunomagnetic beads developed based on this antibody have high sensitivity and good stability, effectively monitoring the level of ActA antibodies in clinical serum samples, and can be used for labeling Listeria monocytogenes.
    Type: Application
    Filed: May 30, 2023
    Publication date: April 3, 2025
    Applicant: Yangzhou University
    Inventors: Xinan JIAO, Yuelan YIN, Mengdi ZHAO, Fanzeng Meng, Xiang CHEN, Jinlin HUANG, Zhiming PAN, Dan GU
  • Patent number: 12256745
    Abstract: A tortoise electric slaughtering device includes an electric slaughtering box, an end of the box is disposed with an outlet, a bottom wall of another end thereof is disposed with a concave area, and a discharging plate is mounted at the outlet. The box is supported on a ground through a frame, and a bottom of the box and an upper surface of the frame have a gap therebetween. A driving wheel rotatably disposed between side walls at one end of the box, a driven wheel rotatably mounted on an end of the frame away from the driving wheel, deflector rollers mounted in a slope direction between side walls of the box at the concave area, and a guiding roller mounted on the box and near the driven wheel, are connected through a conveyer belt. A clamping device is mounted on the box and mounted with a cutting device.
    Type: Grant
    Filed: October 27, 2023
    Date of Patent: March 25, 2025
    Assignee: Yangzhou University
    Inventors: Wenzhi Wei, Chunyu Chen, Zhengcheng Wang
  • Patent number: 12227879
    Abstract: A method for preparing a monodomain liquid crystal elastomer smart fiber incudes: during cross-linking process of the liquid crystal elastomer, drawing of liquid crystal elastomer fibers with uniform diameter from a polymer solution when the viscosity of the cross-linked polymer solution increases to a point where filaments can be drawn; heating by an infrared lamp to form filamentous liquid crystal elastomer fiber; natural air drying to remove excess solvent in the fiber; and stretching and collection of the fiber, followed by placement of the fiber, whereby the monodomain liquid crystal elastomer smart fiber is obtained.
    Type: Grant
    Filed: July 11, 2023
    Date of Patent: February 18, 2025
    Assignees: Changzhou University, Yangzhou University, Yangzhou Technology Innovation Research Center for Carbon Neutrality of Yangzhou University
    Inventors: Ningyi Yuan, Xu Dong, Lvzhou Li, Jianning Ding, Xiaoshuang Zhou, Yaoyao Jiang
  • Patent number: 12085566
    Abstract: The present invention relates to an inert carrier Salmonella and potential use thereof, which is expected to be developed into a new inert carrier bacteria, and can be applied to the development of an indirect agglutination test method for simple and rapid detection of antigens or infected antibodies. The inert carrier Salmonella has been deposited in CGMCC in Beijing on Mar. 18, 2019 with the accession number of CGMCC No.17340, and is classified as Salmonella sp.with a strain code of S9. The Salmonella has no visible agglutination reaction with various chicken sera derived from different genetic backgrounds, i.e., it has no non-specific agglutination reaction with chicken sera derived from broad range of genetic backgrounds.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: September 10, 2024
    Assignee: YANGZHOU UNIVERSITY
    Inventors: Guoqiang Zhu, Bin Yang, Pengpeng Xia, Qiangde Duan, Yang Yang, Xia Meng, Xiaofang Zhu
  • Patent number: 12017956
    Abstract: Disclosed is a method for preparing bittern-carbonization synergistic reinforced recycled aggregate, including the following steps: spray pretreatment: performing alternate spraying on recycled aggregate with bittern and lime milk at intervals for many times at 4-70° C. and a pressure of 0.05-0.6 MPa; carbonization reinforcement: introducing waste gas containing carbon dioxide for a retention time of 4-8 h after the recycled aggregate is allowed to stand for 2-4 h; and rinsing and air drying: removing soluble impurities on a surface of the recycled aggregate by rinsing in water, and performing air-drying on the recycled aggregate to obtain bittern-carbonization synergistic reinforced recycled aggregate. According to the present disclosure, the effective reinforcement of recycled aggregate at normal temperature and pressure in a short time is realized, and the method is simple in process and is convenient in operation.
    Type: Grant
    Filed: February 23, 2024
    Date of Patent: June 25, 2024
    Assignee: Yangzhou University
    Inventors: Changjiang Kou, Jiyang Sun, Zhiwei Sun, Yu Lu, Rongxue Fan, Peng Xiao, Aihong Kang, Zhengguang Wu
  • Publication number: 20240111658
    Abstract: Disclosed are a method and a system for bug localization based on a code knowledge graph, including the steps of: extracting source codes from a Git version control system, parsing in the source codes to generate an abstract syntax tree (AST), constructing a code knowledge graph, preprocessing the summary and description of a bug report crawled from a Bugzilla bug tracking system, and performing the named entity recognition to identify bug-related entity sequence, converting the code knowledge graph and the bug-related entity sequence into vector representation through an embedding algorithm, calculating cosine similarities of vector representations between the code knowledge graph and the bug entity sequence, ranking the similarities from high to low to generate a list of suspicious methods, filtering redundant information in the source codes, identifying bug-related entity elements in the bug report, and reserving the bug-related information.
    Type: Application
    Filed: September 22, 2023
    Publication date: April 4, 2024
    Applicant: YANGZHOU UNIVERSITY
    Inventors: Lili Bo, Zhiwei Zhao, Xiaobing Sun, Yuting He, Xiaoxue Wu, Bin Li
  • Patent number: 11827945
    Abstract: The present invention provides a multiplex PCR detection kit of Listeria monocytogenes serotype 4h. The kit includes a gene Imo1210 detection primer and a gene xysn_1693 detection primer. The present invention establishes a multiplex PCR method for rapidly detecting Listeria monocytogenes serotype 4h by using two pairs of primers.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: November 28, 2023
    Assignee: Yangzhou University
    Inventors: Xin'an Jiao, Yuelan Yin, Youwei Feng, Hao Yao, Xinyu Sun, Zhiming Pan, Xiang Chen, Jing Wang
  • Publication number: 20230354789
    Abstract: An indirect selective breeding method of high-collagen meat geese includes : (1) obtaining a curve equation y=0.017x+0.026; (2) rearing goslings to young geese; (3) measuring the length, width, and height values of the knobs of the geese, and calculating to give the collagen content according to the curve equation obtained in step (1); (4) sorting the geese in descending order according to the collagen content and keeping the geese with collagen content ranked top 50% as breeding geese; (5) after the geese lay eggs, hatching the goose eggs into goslings; and (6) repeating steps (2)-(5) for selective breeding over generations. The indirect selective breeding method is simple and easy to implement. A new strain of meat geese with high collagen content can be obtained from selective breeding simply by measuring the length, width, and height of the knobs of geese of each generation.
    Type: Application
    Filed: May 26, 2022
    Publication date: November 9, 2023
    Applicant: YANGZHOU UNIVERSITY
    Inventors: Yu ZHANG, Qi XU, Yang ZHANG, Zhengfeng CAO, Wangyang JI, Zhixiu WANG, Guohong CHEN, Wenming ZHAO
  • Publication number: 20230292676
    Abstract: Disclosed is an intelligent illumination seedling incubator for sorghum culture. The incubator comprises an incubator body and a culture component. At least one installation opening is formed in the forward side of the incubator body. The culture component comprises culture trays and a vertically arranged connecting shaft which is connected to the incubator body. A plurality of non-circular support pillars are arranged on the connecting shaft at intervals in the height direction. The culture trays are installed in the incubator body through the installation opening. A clamping opening is formed in the culture tray. A connecting sink with the same shape as the support pillar is formed in the downward end of the culture tray inside the clamping opening. After the culture tray is clamped into the connecting shaft through the clamping opening, the culture tray is exactly inserted on the support pillar through the connecting sink.
    Type: Application
    Filed: March 14, 2023
    Publication date: September 21, 2023
    Applicant: YANGZHOU UNIVERSITY
    Inventors: Yanqing WU, Jiao LIU, Guisheng ZHOU
  • Patent number: 11725252
    Abstract: The present disclosure relates to a PCR detection kit for rapidly identifying Salmonella of specific serotypes. The kit includes primers for detecting tcpS gene, the primers for detecting the tcpS gene including a forward primer having a nucleotide sequence as set forth in SEQ ID NO. 1 and a reverse primer having a nucleotide sequence as set forth in SEQ ID NO. 2. The kit can identify Salmonella of enteritidis, pullorum/gallinarum, and dublin serotypes rapidly and in a high throughput, which can be used as an auxiliary method for the conventional serotyping of Salmonella.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: August 15, 2023
    Assignee: YANGZHOU UNIVERSITY
    Inventors: Xinan Jiao, Zhiming Pan, Dan Xiong, Li Song, Yang Jiao, Lin Sun, Xiang Chen, Shizhong Geng, Jinlin Huang, Yuelan Yin
  • Publication number: 20230193194
    Abstract: A generic inert bio-vector Salmonella sp. S9H and potential uses thereof are provided. The generic inert bio-vector Salmonella sp. S9H is derived from a continuous in-vitro culture of an inert bio-vector bacterium Salmonella sp. S9 by using LB solid and liquid culture media for passage to the fortieth generation. With a quantity of bacteria at a working concentration, the S9H does not cause non-specific agglutination reactions in sera or whole blood derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails); moreover, S9H has a property of carrying, and expressing and displaying different antigen factors derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails) on the surface thereof .
    Type: Application
    Filed: December 28, 2020
    Publication date: June 22, 2023
    Applicant: YANGZHOU UNIVERSITY
    Inventors: Guoqiang ZHU, Bin YANG, Yang YANG, Xia MENG, Pengpeng XIA, Qiangde DUAN, Xiaofang ZHU
  • Publication number: 20230147673
    Abstract: The present disclosure provides a recombinant herpesvirus of turkeys (HVT) and a preparation method and use thereof. The present disclosure specifically provides a recombinant HVT, where an exogenous gene is inserted in a spacer region between an HVT005 region and an HVT006 region of an HVT genome; and the exogenous gene is selected from a gene derived from the group consisting of a Newcastle disease virus (NDV), an avian influenza virus (AIV), and an infectious bursal disease virus (IBDV); the spacer region between an HVT005 region and an HVT006 region of an HVT genome is located between 8,867 nt and 9,319 nt of the HVT genome, and has a nucleotide sequence set forth in SEQ ID NO: 1.
    Type: Application
    Filed: April 12, 2022
    Publication date: May 11, 2023
    Applicant: Yangzhou University
    Inventors: Aijian Qin, Xusheng Zai, Bin Shi, Kun Qian, Hongxia Shao, Jianqiang Ye
  • Patent number: 11506218
    Abstract: A method for optimizing the blade axis position of a water pump under all operating conditions which includes determination of multiple calculation conditions within the range of all the operating conditions of the water pump, three-dimensional modeling and mesh generation of the calculation area of the flow field of the water pump at multiple blade angles, numerical simulation of the flow field and calculation and determination of blade hydraulic torques under multiple conditions, determination of the range of the position of the blade resultant hydraulic pressure action line and an optimal blade axis position under all the operating conditions, determination of the small region of the optimal blade axis position under all the operating conditions, determination of the optimal blade axis position, and comparison of the blade hydraulic torques before and after optimization of the blade axis position.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: November 22, 2022
    Assignee: YANGZHOU UNIVERSITY
    Inventors: Baoyun Qiu, Kaiming Wu, Di Liu, Jinyu Cao, Cai Zhang, Chenglong Xue, Mengfan Xu
  • Publication number: 20220307074
    Abstract: The present invention provides a multiplex PCR detection kit of Listeria monocytogenes serotype 4h. The kit includes a gene Imo1210 detection primer and a gene xysn_1693 detection primer. The present invention establishes a multiplex PCR method for rapidly detecting Listeria monocytogenes serotype 4h by using two pairs of primers.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 29, 2022
    Applicant: Yangzhou University
    Inventors: Xin'an JIAO, Yuelan YIN, Youwei FENG, Hao YAO, Xinyu SUN, Zhiming PAN, Xiang CHEN, Jing WANG
  • Patent number: 11386136
    Abstract: Provided is an automatic construction method of a software bug knowledge graph. The method includes extraction of a relationship triple of a bug and domain classification of the bug. Specifically, the method includes: collecting bug information in a bug library and processing bug description information, obtaining a verb phrase and a noun phrase in a description sentence by means of natural language processing, and then obtaining a relationship triple of the bug according to a dependency relationship between words related to the bug information, extracting a domain feature of the bug, performing learning and training with a semi-supervised classifier to enable the classifier automatically to classify unlabeled triples, storing all the classified relationship triples in a graph database, and thus constructing a software bug knowledge graph.
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: July 12, 2022
    Assignee: Yangzhou University
    Inventors: Bin Li, Dingshan Chen, Xiaobing Sun
  • Patent number: 11376319
    Abstract: Provided is a recombinant H7N9 subtype avian influenza virus, a marked vaccine and a preparation method thereof. For the recombinant H7N9 subtype avian influenza virus, a strain JD/17 of H7N9 subtype avian influenza virus is used as parent virus and a peptide sequence in HA protein of the strain JD/17 is replaced with a peptide sequence in HA protein of H3 subtype; the strain JD/17 of H7N9 subtype avian influenza virus has a preservation number of CCTCC No. V201862. The results of HA titers, EID50, TCID50 show that the rescued virus maintains similar biological characteristics of parent virus, such as high HA titers and EID50, and chickens immunized with the marked inactivated and emulsified vaccine produce a high level of antibody, and this antibody can be distinguished from antibodies produced by chickens naturally infected with H7N9 subtype avian influenza virus.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: July 5, 2022
    Assignee: YANGZHOU UNIVERSITY
    Inventors: Daxin Peng, Sujuan Chen, Zhihao Sun, Tao Qin, Qiuxia Wang, Xiufan Liu
  • Publication number: 20220118414
    Abstract: The present invention discloses a method for confined impinging jets (CIJ) mixing with imbalanced momenta. The method includes the following steps: connecting each inlet of a CIJ mixer with a to-be-mixed fluid by using an inlet conduit; connecting an outlet of the mixer with an inlet of a suction device by using an outlet conduit; and starting the suction device, enabling the to-be-mixed fluids to enter the mixer sequentially through the conduits and the inlets of the mixer and to mix in a mixer chamber, and the mixture is then sucked out from the outlet of the mixer and flows sequentially through the conduit, the inlet of the suction device, and the outlet of the suction device.
    Type: Application
    Filed: December 29, 2021
    Publication date: April 21, 2022
    Applicants: YANGZHOU UNIVERSITY
    Inventor: Zhengxi ZHU
  • Patent number: 11299903
    Abstract: A prestress-free self-centering energy-dissipative tension-only brace, including a self-centering mechanism, an energy dissipation mechanism, a force-limiting energy-dissipative mechanism, a high strength steel cable, and a sleeve. The self-centering mechanism includes a sliding end plate, a spring, and a connection rod. One end of the spring is connected and fixed to the inner wall of the sleeve, and the other end of the spring is connected with the sliding end plate. One end of the connection rod is anchored at the center of the sliding end plate, and the other end of the connection rod passes through a fixed end of the spring. The energy dissipation mechanism includes rotating shafts, rotating wheels, friction plates, chains, and a cross-shaped connecting piece.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: April 12, 2022
    Assignee: YANGZHOU UNIVERSITY
    Inventors: Pei Chi, Wenlong Tian, Dafu Cao, Kun Wang, Tong Xing
  • Publication number: 20220043845
    Abstract: Disclosed is a template-based automatic question and answer method for software bug. An entity relationship triple is extracted from a bug corpus and a natural language pattern is acquired; an entity relationship in the triple is determined; a query template corresponding to the natural language pattern is acquired; an entity in a question q proposed by a user is replaced with an entity type to acquire a question q?; then, the entity type in q? and an entity type in the natural language pattern are compared and searched for and a similarity is calculated; then, a SPARQL query pattern of the question q is acquired according to the similarity and the entity in the question q; and finally, the SPARQL query pattern of the question q is executed so as to acquire an answer to the question q.
    Type: Application
    Filed: August 28, 2019
    Publication date: February 10, 2022
    Applicant: Yangzhou University
    Inventors: Xiaobing SUN, Jinting LU, Bin LI