Patents Assigned to YEDÍTEPE ÜNÍVERSÍTESÍ
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Publication number: 20190343886Abstract: A composition inhibiting MEIS proteins. The MEIS proteins are effective in proliferation of hematopoietic stem cells. A formulation capable of easily passing through the cell membrane and perform its activity in the cell, and can inhibit MEIS activity in a dose dependent manner. The combination includes isolated cells, medium, growth factors and MEISi inhibitor. The isolated cells are isolated from mouse bone marrow, human bone marrow and human umbilical cord blood. The medium has a pH value of 7.2 and contains bovine serum albumin, recombinant insulin, transferrin, 2-mercaptoethanol and IMDM medium. The growth factors are hematopoietic stem cell factor SCF, fetus liver tyrosine kinase-3 ligand Flt3L, and thrombopoietin. A chemical formula of the MEISi-1 is 4-[2-(benzylamino)-2-oxoethoxy]-N-(2,3-dimethylphenyl) benzamide. A chemical formula of MEISi-2 is 4-hydroxy-N?-[(Z)-(2-oxonaphthalen-1-ylidene)methyl] benzohydrazide.Type: ApplicationFiled: September 25, 2017Publication date: November 14, 2019Applicant: YEDÍTEPE ÜNÍVERSÍTESÍInventors: Fatih KOCABAS, Raife Dilek TURAN
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Patent number: 10125453Abstract: The present invention relates to a method of obtaining antifungal, anticandidal and antibacterial textile products. The objective of the present invention is to obtain an antimicrobial product, which enables to reduce the infectious diseases that are transmitted or spread by textile products, reduces extra cost and energy spent for ensuring hygiene, and increases hygienity of disposable textile products. A solution of triclosan, chlorhexidine and disodium octaborate pentahydrate is used in the method of the present invention. The said solution enables the hydrophobic textile products to be transformed into hydrophilic products and thereby enables the antimicrobial agents in the solution to be coded into the textile products.Type: GrantFiled: August 14, 2014Date of Patent: November 13, 2018Assignee: YEDITEPE ÜNIVERSITESIInventors: Fikrettin Sahin, Selami Demirci, Okan Demir, Zeynep Ustaoglu
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Patent number: 9943076Abstract: The present invention relates to a cryopreservation (freezing) medium which can be used for long-term storage of cell lines, tissue samples, sperms, oocytes and embryos. The invention enables to freeze and store cells without affecting cell viability, to increase cell viability and to protect multipotent properties of the cells. The invention facilitates freezing and storing sperms, eggs, embryos, plant cells and materials, cancer and sensitive cell lines, stem cells (embryonic and mesenchymal), blood and blood cells and biological material and organs.Type: GrantFiled: August 13, 2014Date of Patent: April 17, 2018Assignee: YEDITEPE ÜNIVERSITESIInventors: Fikrettin Sahin, Selami Demirci, Aysegul Dogan
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Publication number: 20160215442Abstract: The present invention relates to a method of obtaining antifungal, anticandidal and antibacterial textile products. The objective of the present invention is to obtain an antimicrobial product, which enables to reduce the infectious diseases that are transmitted or spread by textile products, reduces extra cost and energy spent for ensuring hygiene, and increases hygienity of disposable textile products. A solution of triclosan, chlorhexidin and disodium octaborate pentahydrate is used in the method of the present invention. The said solution enables the hydrophobic textile products to be transformed into hydrophilic products and thereby enables the antimicrobial agents in the solution to be coded into the textile products.Type: ApplicationFiled: August 14, 2014Publication date: July 28, 2016Applicant: YEDITEPE ÜNIVERSITESIInventors: Fikrettin SAHIN, Selami DEMIRCI, Okan DEMIR, Zeynep USTAOGLU
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Publication number: 20160205922Abstract: The present invention relates to a cryopreservation (freezing) medium which can be used for long-term storage of cell lines, tissue samples, sperms, oocytes and embryos. The invention enables to freeze and store cells without affecting cell viability, to increase cell viability and to protect multipotent properties of the cells. The invention facilitates freezing and storing sperms, eggs, embryos, plant cells and materials, cancer and sensitive cell lines, stem cells (embryonic and mesenchymal), blood and blood cells and biological material and organs.Type: ApplicationFiled: August 13, 2014Publication date: July 21, 2016Applicant: YEDITEPE ÜNIVERSITESIInventors: Fikrettin SAHIN, Selami DEMIRCI, Aysegul DOGAN