Patents Assigned to Yeda Research and Development Company Limited
  • Patent number: 4962255
    Abstract: A method of selective beta-alkylation of aromatic substrates such as naphthalene or a derivative thereof, comprising reacting the substrate with an alcohol or olefin alkylating agent in the presence of a catalyst selected from the group consisting of a crystallized borosilicate glass zeolite and a crystalline alumina-silica catalyst, said catalyst being at least 86% beta selective with respect to the alkylation of naphthalene by the alkylating agent.
    Type: Grant
    Filed: March 6, 1989
    Date of Patent: October 9, 1990
    Assignee: Yeda Research & Development Company Limited
    Inventors: Dan Fraenkel, Moshe Levy, Baruch Ittah, Margaret Cherniavsky
  • Patent number: 4933970
    Abstract: A method and apparatus are disclosed and claimed which enable an entity to generate proofs of identity and signatures of messages that everyone can verify but no one can forge. Compared to other schemes of this type (such as the RSA), the Fiat-Shamir scheme is faster by one to two orders of magnitude. In the present invention disclosed and claimed in this patent application, two improved variants of the Fiat-Shamir scheme are described which are even faster. One variant uses small public values to optimize the vertification procedure, and the other variant uses particular secret values to optimize the generation procedure.
    Type: Grant
    Filed: January 19, 1988
    Date of Patent: June 12, 1990
    Assignee: Yeda Research and Development Company Limited
    Inventor: Adi Shamir
  • Patent number: 4932056
    Abstract: A method and apparatus for identification of a prover to a verifier in which the prover demonstrates his knowledge of a secret permutation .pi. such that V.sub..pi. .epsilon. K(A) for publicly known A and V where all the arithmetic operations are carried out modulo p. The actual proof does not reveal any knowledge of .pi., and thus it cannot be misused by dishonest verifiers or eavesdroppers to later misrepresent themselves as the prover. The new scheme is much faster than the RSA and Fiat-Shamir identification schemes.
    Type: Grant
    Filed: March 16, 1989
    Date of Patent: June 5, 1990
    Assignee: Yeda Research and Development Company Limited
    Inventor: Adi Shamir
  • Patent number: 4882318
    Abstract: The invention relates to pharmaceutical compositions intended to decrease the incidence of tumor metastasis in patients who suffer from malignant diseases.The pharmaceutical compositions of the invention contain as active ingredient heparin or a suitable derivative thereof. Amongst suitable derivatives are N-desulfated and N-acetylated heparin.The dosage of the administered heparin or heparin derivative is quite critical and will generally be in the range of from 0.05 mg/kg/day to about 0.5 mg/kg/day. A preferred range is between about 0.1 mg/kg/day to about 0.5 mg/kg/day.
    Type: Grant
    Filed: June 24, 1987
    Date of Patent: November 21, 1989
    Assignees: Hadassa Medical Organization, Yeda Research and Development Company Limited
    Inventors: Israel Vlodavsky, Amiram Eldor, Yaakov Naparstek, Irun R. Cohen
  • Patent number: 4835326
    Abstract: The invention relates to the stabilization of monobromostyrene of dibromostyrene and of mixtures of these. The stabilization is effected by means of hydroxy-benzene derivatives, where the benzene ring contains at least two substituents, one of these being a hydroxy group. The process is advantageously carried out by heating the styrene material with an excess of the inhibitor, distilling the monomer and adding an additional quantity of the inhibitor. The distilled monomer is preferably dried prior to the addition of the further quantity of inhibitor.
    Type: Grant
    Filed: July 20, 1987
    Date of Patent: May 30, 1989
    Assignee: Yeda Research and Development Company Limited
    Inventors: Stephen L. J. Daren, David Vofsi, Michael Peled
  • Patent number: 4822949
    Abstract: The invention relates to the production of F.sub.1 hybrid seeds in cucumber (Cucumis sativus). The present invention relates to a method wherein the pollen-parent bears only male flowers and thus lacks the capability to bear fruits. The method comprises planting the hybrid seed production field with a mixture of seed-parent and pollen-parent seeds and harvesting the desired F.sub.1 hybrid cucumber seeds from the thus produced fruit on the seed parent.This invention also relates to hybrid seed produced by the methods of this invention, the hybrid cucumber plant produced from the hybrid cucumber seed, and variants, modifications, and mutants thereof.
    Type: Grant
    Filed: April 20, 1987
    Date of Patent: April 18, 1989
    Assignee: Yeda Research Development Company Limited
    Inventors: Shlomo Niego, Esra Galun, Margalith Levy
  • Patent number: 4806393
    Abstract: To plasticized polyvinyl chloride (PVC) there is applied a layer of PVC modified by the introduction of functional groups which can be crosslinked, preferably under the influence of heat. Such crosslinking provides a thin coating which prevents leakage of plasticizer and additives from the plasticized PVC substrate when it is contacted with solvents. Preferred modification of the PVC is by means of thiocarbamate moieties replacing some of the chlorine in the PVC from which the surface layer is produced.
    Type: Grant
    Filed: March 25, 1987
    Date of Patent: February 21, 1989
    Assignee: Yeda Research and Development Company Limited
    Inventor: Gideon Levin
  • Patent number: 4799141
    Abstract: An electronic controller connectible to an external system comprises: a plurality of logical networks each capable of assuming a plurality of different states and arranged according to a hierarchy of different networks according to a hierarchy of different states having a one-to-one mapping between states and networks such that any transition between two states affects the two associate networks and their respective lower-order networks. Each of the logical networks includes a storage element for storing its state, means for determining its next state, and means for receiving control signals from, or for outputting control signals to, the immediately higher level logical network and the immediately lower level logical network for determining their respective states. At least some of the logical networks include means for receiving control signals from, or for outputting control signals to, the external system.
    Type: Grant
    Filed: April 9, 1987
    Date of Patent: January 17, 1989
    Assignee: Yeda Research and Development Company Limited
    Inventors: Doron Drusinsky, David Harel
  • Patent number: 4748668
    Abstract: A method and apparatus for simple identification and signature which enable any user to prove his identity and the authenticity of his messages to any other user. The method and apparatus are provably secure against any known or chosen message attack if factoring is difficult, and require only 1% to 4% of the number of modular multiplications previously required. The simplicity, security and speed of the method and apparatus derive from microprocessor-based devices which may be incorporated into smart cards, personal computers, passports, and remote control systems.
    Type: Grant
    Filed: July 9, 1986
    Date of Patent: May 31, 1988
    Assignee: Yeda Research and Development Company Limited
    Inventors: Adi Shamir, Amos Fiat
  • Patent number: 4735997
    Abstract: There are provided polymers containing amido-thiolate groups. These are produced by a nuceophilic substitution of polymers containing chlorine, and the resulting polymers have a pronounced hydrophylic character. There is also provided a process for the production of these starting with polymers which contain chlorine in the polymeric backbone or in side chains.
    Type: Grant
    Filed: November 7, 1985
    Date of Patent: April 5, 1988
    Assignee: Yeda Research & Development Company Limited
    Inventors: Gideon Levin, Hemi N. Nae
  • Patent number: 4652519
    Abstract: There are provided bifunctional chelating agents, which are analogues of EDTA, conjugates of same with a variety of haptens and conjugates of such conjugates with haptens with certain metals, forming metal complexes. The metal complexes have a variety of uses, among these various assays for the determination of haptens and macromolecules. There is also provided a process for the production of the above. There are provided radioimmunoassays based on the above conjugates with metal cations.
    Type: Grant
    Filed: January 27, 1984
    Date of Patent: March 24, 1987
    Assignee: Yeda Research and Development Company Limited
    Inventors: Abraham Warshawsky, Meir Wilchek, Janina Altman, Nurit Shoef
  • Patent number: 4624923
    Abstract: A metal-containing polyaldehyde microsphere composed of a polyaldehyde microsphere to which a transition metal, e.g. Au, Ag, Pt, Pd, Tc, Fe, Ni or Co, is bound may be obtained in accordance with this invention. The polyaldehyde, e.g. polyacrolein or polyglutaraldehyde, may be encapsulated in agarose, and the microsphere may be radioactive or magnetic. The microphere may additionally have a compound having at least one amine group, e.g. a drug, antibody, antigen, enzyme or other protein, bound to its surface.In one embodiment a transition metal is bound to a polyaldehyde microsphere by contacting the polyaldehyde microsphere with a suitable amount of an appropriate salt or acid of the transition metal under suitable conditions so as to cause the salt or acid to be reduced to a lower valence state and to bind to the microsphere. Some salts or acids may thus be reduced to the elemental state; others are further reduced with an appropriate reducing agent.
    Type: Grant
    Filed: January 24, 1986
    Date of Patent: November 25, 1986
    Assignee: Yeda Research and Development Company Limited
    Inventor: Shlomo Margel
  • Patent number: 4562133
    Abstract: There are provided photoconductive compounds wherein 3-substituted N-alkyl carbazole groups and 3,5-dinitrobenzoic acid moieties are attached directly or via spacer groups to a polymeric backbone. The photoconductive compounds can be used in devices based on the photoconductivity of such compounds, such as sensors or the like, said compounds being used in the form of a film or a coating. The maximum sensitivity of such sensors is in the IR region.
    Type: Grant
    Filed: October 4, 1984
    Date of Patent: December 31, 1985
    Assignee: Yeda Research and Development Company Limited
    Inventor: Almeria Natansohn
  • Patent number: 4250084
    Abstract: Chemically substantially pure and uniform THF (thymic hormone), substantially devoid of endotoxins, having a molecular weight of 3323.sup..+-. 220, an isoelectric point of from 5.7 to 5.
    Type: Grant
    Filed: September 18, 1978
    Date of Patent: February 10, 1981
    Assignee: Yeda Research and Development Company Limited
    Inventor: Nathan Trainin