Patents Assigned to Yield10 Bioscience, Inc.
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Patent number: 12084672Abstract: A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression (“an ISY protein”) is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein of Camelina sativa comprising SEQ ID NO: 2 or a fragment, Camelina sativa homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.Type: GrantFiled: September 3, 2019Date of Patent: September 10, 2024Assignee: Yield10 Bioscience, Inc.Inventors: Jihong Tang, Meghna Malik, Nirmala Sharma, Claire Burkitt, Yuanyuan Ji, Madana M. R. Ambavaram, Kieran Ryan, Oliver P. Peoples, Kristi D. Snell, Frank Anthony Skraly, Venkatesh Bollina
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Patent number: 11965182Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are unprecedented.Type: GrantFiled: October 11, 2021Date of Patent: April 23, 2024Assignee: YIELD10 BIOSCIENCE, INC.Inventors: Meghna Malik, Jihong Tang, Kristi D. Snell
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Patent number: 11834666Abstract: A genetically engineered land plant that expresses a plant CCP1-like mitochondrial transporter protein is provided. The genetically engineered land plant comprises a modified gene for the plant CCP1-like mitochondrial transporter protein. The plant CCP1-like mitochondrial transporter protein is an ortholog of CCP1 of Chlamydomonas reinhardtii of SEQ ID NO: 1 derived from a source land plant. The plant CCP1-like mitochondrial transporter protein is localized to mitochondria of the genetically engineered land plant based on a mitochondrial targeting signal intrinsic to the plant CCP1-like mitochondrial transporter protein. The modified gene comprises (i) a promoter and (ii) a nucleic acid sequence encoding the plant CCP1-like mitochondrial transporter protein. The promoter is non-cognate with respect to the nucleic acid sequence.Type: GrantFiled: June 15, 2018Date of Patent: December 5, 2023Assignee: YIELD10 BIOSCIENCE, INC.Inventors: Frank Anthony Skraly, Oliver P. Peoples, Kristi D. Snell, Meghna Malik
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Patent number: 11746356Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.Type: GrantFiled: March 24, 2021Date of Patent: September 5, 2023Assignee: YIELD10 BIOSCIENCE, INC.Inventors: Madana M. R. Ambavaram, Mariya Somleva
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Patent number: 11174467Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are simply unprecedented.Type: GrantFiled: April 8, 2016Date of Patent: November 16, 2021Assignee: YIELD10 BIOSCIENCE, INC.Inventors: Meghna Malik, Jihong Tang, Kristi D. Snell
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Patent number: 11072798Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.Type: GrantFiled: September 13, 2019Date of Patent: July 27, 2021Assignee: YIELD 10 BIOSCIENCE, INC.Inventors: Madana M. R. Ambavaram, Mariya Somleva
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Publication number: 20190338302Abstract: A transgenic land plant is provided. The transgenic land plant comprises a putative bicarbonate transporter protein of an edible eukaryotic algae. The putative bicarbonate transporter protein of the edible eukaryotic algae is heterologous with respect to the transgenic land plant. The putative bicarbonate transporter protein is an ortholog of CCP1 of Chlamydomonas reinhardtii of SEQ ID NO: 1. The putative bicarbonate transporter protein is localized to mitochondria of the transgenic land plant based on a mitochondrial targeting signal intrinsic to the putative bicarbonate transporter protein.Type: ApplicationFiled: February 3, 2017Publication date: November 7, 2019Applicant: Yield10 Bioscience, Inc.Inventors: Oliver P. Peoples, Kristi D. Snell, Meghna Malik
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Patent number: 10450580Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.Type: GrantFiled: February 15, 2018Date of Patent: October 22, 2019Assignee: Yield10 Bioscience, Inc.Inventors: Madana M.R. Ambavaram, Mariya Somleva