Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are unprecedented.
Type:
Grant
Filed:
October 11, 2021
Date of Patent:
April 23, 2024
Assignee:
YIELD10 BIOSCIENCE, INC.
Inventors:
Meghna Malik, Jihong Tang, Kristi D. Snell
Abstract: A genetically engineered land plant that expresses a plant CCP1-like mitochondrial transporter protein is provided. The genetically engineered land plant comprises a modified gene for the plant CCP1-like mitochondrial transporter protein. The plant CCP1-like mitochondrial transporter protein is an ortholog of CCP1 of Chlamydomonas reinhardtii of SEQ ID NO: 1 derived from a source land plant. The plant CCP1-like mitochondrial transporter protein is localized to mitochondria of the genetically engineered land plant based on a mitochondrial targeting signal intrinsic to the plant CCP1-like mitochondrial transporter protein. The modified gene comprises (i) a promoter and (ii) a nucleic acid sequence encoding the plant CCP1-like mitochondrial transporter protein. The promoter is non-cognate with respect to the nucleic acid sequence.
Type:
Grant
Filed:
June 15, 2018
Date of Patent:
December 5, 2023
Assignee:
YIELD10 BIOSCIENCE, INC.
Inventors:
Frank Anthony Skraly, Oliver P. Peoples, Kristi D. Snell, Meghna Malik
Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are simply unprecedented.
Type:
Grant
Filed:
April 8, 2016
Date of Patent:
November 16, 2021
Assignee:
YIELD10 BIOSCIENCE, INC.
Inventors:
Meghna Malik, Jihong Tang, Kristi D. Snell
Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
Abstract: A transgenic land plant is provided. The transgenic land plant comprises a putative bicarbonate transporter protein of an edible eukaryotic algae. The putative bicarbonate transporter protein of the edible eukaryotic algae is heterologous with respect to the transgenic land plant. The putative bicarbonate transporter protein is an ortholog of CCP1 of Chlamydomonas reinhardtii of SEQ ID NO: 1. The putative bicarbonate transporter protein is localized to mitochondria of the transgenic land plant based on a mitochondrial targeting signal intrinsic to the putative bicarbonate transporter protein.
Type:
Application
Filed:
February 3, 2017
Publication date:
November 7, 2019
Applicant:
Yield10 Bioscience, Inc.
Inventors:
Oliver P. Peoples, Kristi D. Snell, Meghna Malik
Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.