Abstract: A colloid solution for preparing a suspension, containing one or more components selected from Group A and one or more components selected from Group B as dispersoids, and water as a dispersant medium, the colloid solution being at a pH such that suspensoid particles added thereto are positively charged; wherein Group A consists of xylitol, D-sorbitol, D-mannitol, lactose, saccharose, cyclodextrin, maltose, D-fructose, D-glucose and galactose; and Group B consists of sodium carboxymethylcellulose, sodium alginate, sodium polyacrylate and gum arabic.
Type:
Grant
Filed:
March 4, 1988
Date of Patent:
January 19, 1993
Assignees:
Yoshiaki Kawashima, Showa Yakuhin Kako Co., Ltd.
Abstract: A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
Type:
Grant
Filed:
September 20, 1990
Date of Patent:
February 11, 1992
Assignees:
Showa Yakuhin Kako Co. Ltd., Yoshiaki Kawashima
Inventors:
Toshiyuki Niwa, Yoshiaki Kawashima, Hirofumi Takeuchi, Yoji Ito
Abstract: A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in the shell, which mainly consists of an enteron-soluble polymer. The method for preparing the medicine includes the steps of: (a) mixing a hydrophilic or hydrophobic drug with an enteron-soluble polymer in a mixture of an aliphatic alcohol and a chlorohydrocarbon; and (b) pouring this mixture into water or an aqueous medium, and stirring the solution to precipitate the medicine.
Type:
Grant
Filed:
June 19, 1989
Date of Patent:
October 15, 1991
Assignees:
Showa Yakuhin Kako Co., Ltd., Yoshiaki Kawashima
Inventors:
Toshiyuki Niwa, Yoshiaki Kawashima, Hirofumi Takeuchi, Yoji Ito