Patents Assigned to Yoshitomo Pharmaceutical Industries, Ltd.
  • Process for purifying recombinant human serum albumin
    Patent number: 5962649
    Abstract: The invention provides a process for purifying recombinant human serum albumin (rHSA) by heating a culture medium containing rHSA and the rHSA-producing host cello, feeding said heated solution upwardly into a fluidized bed in which adsorbent particles are suspended to effect contacting with the adsorbent particles and then recovering the adsorbed fraction containing the rHSA, and a composition comprising rHSA which shows a A35D/A280 ratio of below 0.015, when formulated into a 25% solution of said albumin.
    Type: Grant
    Filed: August 31, 1995
    Date of Patent: October 5, 1999
    Assignee: Yoshitomo Pharmaceutical Industries, Ltd.
    Inventors: Munehiro Noda, Akinori Sumi, Takao Ohmura, Kazumasa Yokoyama