Patents Assigned to Yukong Limited
  • Patent number: 6031119
    Abstract: Polyalkylene guanidine salts or polyalkylene biguanidine salts having a branched silane compound of formula I show excellent antimicrobial activity and can be applied to various materials including fibers, wood, paper, glass, resins and metals: ##STR1## wherein A is oxyethylene, oxypropylene, oxybutylene, oxystyrene, diphenylsulfone, diphenyl sulfide or alkylamide, which repeating number is 1 to 100,000, or straight or branched alkyl chain containing 1 to 20 carbon atoms;Y represents a blank, HCl, HBr, HI, HNO.sub.
    Type: Grant
    Filed: July 8, 1997
    Date of Patent: February 29, 2000
    Assignee: Yukong Limited
    Inventors: Byung-Hyoung Lee, Woo-Sun Kim, Young-Jun Kim, Sang-Gu Bang, Kwang-Min Lim, Sang-Rak Choi, Keum-Chan Joo
  • Patent number: 5958368
    Abstract: Noncrystalline mesoporous molecular sieve substances are prepared using alkyltrimethylammonium halide as a surfactant in combination with water-soluble organic or inorganic salts capable of binding to a monovalent cation. The sieve substances are superior to the M41S series in thermal stability and hydrothermal stability. The sieve substances are structurized in such a manner that channels uniform in diameter are randomly arranged interconnecting with one another in a three-dimensional way so as to allow reactants to readily diffuse therein.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: September 28, 1999
    Assignee: YuKong Limited
    Inventors: Ryong Ryoo, Ji Man Kim
  • Patent number: 5955499
    Abstract: O-carbamoyl-(D/L )-phenylalaninol represented by structural formula I is pharmaceutically useful to treat diseases of the central nervous system, which is prepared by a characteristic process comprising the steps of: treating phenylalaninol with benzyl chloroformate in a basic aqueous solution medium, to give N-benzyloxycarbonyl-phenylalaninol; subjecting this intermediate to reaction with phosgene and then, to the treatment with excess of concentrated ammonium hydroxide aqueous solution, to provide O-carbamoyl-N-benzyloxycarbonyl-phenylalaninol; deprotecting it through hydrogenolysis reaction.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: September 21, 1999
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Jai Kook Byun
  • Patent number: 5935997
    Abstract: The present invention relates to O-thiocarbamoyl-aminoalkanol compound represented by the following structural formula (VI), (VIII) and (IX) which are a racemic or enantiomerically enriched and pharmaceulically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein Ar is a phenyl group as described as follows: ##STR2## wherein R is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br, and I, alkoxy containing 1 to 3 carbon atoms, thioalkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, or taifluorocarbon, and x is an integer from 1 to 3, with the proviso that R is the same or different when x is 2 or 3. R.sub.1 and R.sub.2 may be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, 3 to 7-membered aliphatic cyclic compounds and R.sub.1 and R.sub.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: August 10, 1999
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Yong Kil Kim
  • Patent number: 5932181
    Abstract: A natural gas-using hydrogen generator is provided which is able to produce high purity hydrogen from natural gas and water. The generator comprises a desulfurization reactor, a reformer and a PSA. The natural gas-using hydrogen generator also comprises a first pipe line for connecting the reformer with the desulfurization reactor to provide hot combustion gas from the reformer to the desulfurization reactor. A first valve controls air flow being fed to the reformer, which is provided on a second pipe line for feeding air into the reformer. A heat exchanger is provided for exchanging heat between a third pipe line, whose both ends are connected to the second pipe line with the first valve therebetween. A fourth pipe line leads a hot product gas from the reformer to the CO conversion reactor to cool the product gas. A second valve, provided on the third pipe line, controls air flow being fed to the third pipe line.
    Type: Grant
    Filed: December 10, 1997
    Date of Patent: August 3, 1999
    Assignee: Yukong Limited
    Inventors: Tae Chun Kim, Kyung Shick Yoon, Seong Jae Jeong, Jae Sung Han, Joon Ho Hyoung
  • Patent number: 5908769
    Abstract: An ester compound is prepared with a greatly improved efficiency by reacting a liquid alcohol with a liquid organic acid at a temperature of about 30 to 70.degree. C. in the presence of a lipase without adding any solvent. In particular, short chain acids and alcohols are reacted with lipase from candida antarctica immobilized on an acrylic resin.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: June 1, 1999
    Assignee: Yukong Limited
    Inventors: Byung Hyung Lee, Soon Ook Hwang, Nam Ryun Cho
  • Patent number: 5892088
    Abstract: There are disclosed novel sulfamate compounds containing N-substituted carbomoyl group including their racemates and (R)- and (S)-optical isomers represented by Formulas I, II and III, pharmaceutically useful for the prophylaxis and treatment of the disorders of the central nervous system, especially for nervous myalgia, epilepsy and minimal brain dysfunction: ##STR1## (III).
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: April 6, 1999
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Dong Il Han, Hyung Cheol Kim
  • Patent number: 5882932
    Abstract: A continuous, quick measurement method of BOD, and an apparatus therefor is disclosed. The apparatus comprises a sample tank in which a sample is prepared suitably for the measurement, a reactor in which microorganisms maintain their activity, a medium reservoir which contains nutrients for the growth of the microorganisms, pumps for transferring liquids, and a microprocessor which controls the operation of all means including a magnetic stirrer for mixing the liquid in the reactor and diagnoses of the apparatus itself. Using the apparatus, the method comprises a continuous culture stage, an endogenous respiration stage, a endogenous respiration rate-measuring stage, a sample feeding stage and a BODq measuring stage. The apparatus can detect BOD in one hour and is very low in error rate. Further, because microorganisms can be continuously cultured, the apparatus is semi-permanent, easy to manage, low in cost and suitable to be operated at a treatment site.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: March 16, 1999
    Assignee: Yukong Limited
    Inventors: Kyung Shick Yoon, Yong Seok Park, Hyung Charn Kim, Yong Teak Yi, Yeal Soon Hwang, Sung Yoon Kang, Ki Nom Chung, Jin Cheol Kim
  • Patent number: 5861461
    Abstract: A plastic composition superior in both biodegradability and physical properties, comprises a matrix resin which is a blend of polyethylene and a biodegradable aliphatic polyester, starch, a coupling agent, a radical initiator, a starch plasticizer, a starch destructurizing agent and an autooxidizing agent, wherein the starch chemically binds to the matrix resin.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: January 19, 1999
    Assignee: Yukong Limited
    Inventors: Byung Hyung Lee, Kwang Sik Jung, Young Wook Kim, Sang Gu Bang, Won Young Cho, Byoung Cheon Jo, Ki Nam Uhm
  • Patent number: 5854283
    Abstract: The optically pure forms of monoocarbamates of halogenated 2-phenyl-1,2-ethanediol and dicarbamates of 2-phenly-1,2-ethaniediol have been found to be effective in the treatment of disorders of the central nervous system, especially as anti-convulsive or anti-epileptic agents.
    Type: Grant
    Filed: January 9, 1997
    Date of Patent: December 29, 1998
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Min Woo Kim, Jeonghan Park
  • Patent number: 5849772
    Abstract: (S)-2-Aryl-1,3-propanediol monocarbamate and its intermediate, (S)-3-acetoxy-2-aryl-propanol carbamate, represented by the following formulas I and II, respectively, have pharmaceutically useful activity against for central nervous system disorders including nervous myalgia, epilepsy and cerebral apoplexy: ##STR1## wherein, R is ##STR2## wherein X is an oxygen atom or a sulfur atom; and Y represents a halogen element, trifluoromethyl, or a lower alkyl group containing one to three carbon atoms.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: December 15, 1998
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Dong Il Han, Kwang Hyouk Lee, Hyung Cheol Kim
  • Patent number: 5840643
    Abstract: A method for separating oxidation catalysts used for producing trimellitic acid, which comprises the steps of: adding water to a reactor effluent in a volume ratio of water to the reactor effluent of 0:1 to 11:1, the reactor effluent being in a slurry state and resulting from oxidizing pseudocumene with air in an acetic acid and in the presence of cobalt, manganese and bromine catalysts; heating the mixture of water and the reactor effluent to a temperature of 25.degree. to 140.degree. C. to make the slurry be a diluted reactor effluent in a liquid phase; passing the diluted reactor effluent through ion exchange resins, to adsorb cobalt, manganese and bromine ions on the resins; regenerating the resins with an eluting solution; and isolating the oxidation catalysts from an effluent, shows recoveries of at least 99 wt % for cobalt, at least 99 wt % for manganese and at least 90 wt % for bromine.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: November 24, 1998
    Assignee: Yukong Limited
    Inventors: Sang-hoon Park, Jae-young Bae, Young-sam Kim, Jae-eun Kim
  • Patent number: 5817858
    Abstract: There is disclosed 3-N-substituted thiocarbamoyl-2-phenyl-1,3-propanediol carbamate, represented by the following structural formula I, that is very effective for prophylaxis and treatment of central nervous system disorders including nervous muscular pain, epilepsy and cerebral apoplexy: ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 8 carbon atoms and 5 to 7-membered aliphatic cyclic compound which may comprise two or less nitrogen or oxygen atoms directly unconnected, with a proviso that R.sub.1 and R.sub.2 both should not be hydrogen and the total number of carbon atoms of R.sub.1 and R.sub.2 ranges from 1 to 16.
    Type: Grant
    Filed: April 9, 1996
    Date of Patent: October 6, 1998
    Assignee: Yukong Limited
    Inventors: Choi Yong Moon, Han Dong Il, Kim Hyung Cheol
  • Patent number: 5756817
    Abstract: The present invention relates to a racemic or enantiomerically enriched O-carbamoyl-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein Ph is a phenyl group as described as follows: ##STR2## wherein R is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms, and x is an integer from 1 to 3, with the proviso that R is the same or different when x is 2 or 3, R.sup.1 and R.sup.2 may be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cyclic propyl and 5 to 7-membered aliphatic cyclic compounds, and R.sup.1 and R.sup.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: May 26, 1998
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Dong Il Han, Yong Kil Kim, Hun Woo Shin, Jeong-Han Park
  • Patent number: 5714545
    Abstract: A thermoplastic elastomeric composition, which comprises liquid 1,2-polybutadiene, EPDM rubber, a polyolefin resin, a curative system consisting of phenolic resin and peroxide, and a co-curing agent, the 1,2-polybutadiene and EPDM rubber being at least partially cured, shows well-balanced various properties including physical properties, elasticity and thermal resistance in addition to being superior in oil resistance at high temperatures and processability.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: February 3, 1998
    Assignee: Yukong Limited
    Inventors: Soon Jong Lee, Hae Won Lee, Dong Jin Chu, Kyu Jong Lee, Byung Hyung Lee
  • Patent number: 5705640
    Abstract: The present invention relates to O-carbamoyl-(D)-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein R.sup.1 and R.sup.2 may be the same with or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 8 carbon atoms, and 5 to 7-membered aliphatic cyclic compounds which may comprise not more than two nitrogen or oxygen atoms directly unconnected, the total number of carbon atom of R.sup.1 and R.sup.2 ranging from 0 to 16.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: January 6, 1998
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Dong Il Han, Yong Kil Kim
  • Patent number: 5698588
    Abstract: The pure enantiomeric forms, as well as enantiomeric mixtures excluding the racemic mixture of monocarbamates of 2-phenyl-1,2-ethanediol substituted with more than one halogen atom on the phenyl ring and dicarbamates of 2-phenyl-1,2-ethanediol substituted with more than one halogen atom on the phenyl ring have been found to be effective in the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: December 16, 1997
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Min Woo Kim
  • Patent number: 5654461
    Abstract: 3-O-Carbamoyl-2-phenyl-1,3-propanediol sulfamate racemate, represented by the following structural formula I: ##STR1## and its (R)- and (S)-optical isomers, which are very effective for prophylaxis and the treatment of central nervous system disorders including nervous muscular pain, epilepsy and minimal brain dysfunctions, are disclosed. They are prepared from 2-phenyl-1,3-propanediol monocarbamate and its optical isomers, respectively.
    Type: Grant
    Filed: March 14, 1996
    Date of Patent: August 5, 1997
    Assignee: Yukong Limited
    Inventors: Yong Moon Choi, Dong Il Han, Hyung Cheol Kim
  • Patent number: 5627282
    Abstract: This invention relates to the preparation of optically pure tetrahydro-3-isoquinolinecarboxylic acid derivative of formula (III) which comprises the reaction of optically pure phenylalanine derivative of formula (I) with a formaldehyde precursor, such as formaline, trioxane, dialkoxymethane, or paraformaldehyde, for about 10 hours to 60 hours at about 40 .degree. C. to about 60 .degree. C. in concentrated hydrochloric acid to give the compound of formula (II), followed by neutralization in hot water at about 70 .degree. C. to about 100 .degree. C. with a base, such as ammonium hydroxide, potassium carbonate, sodium carbonate, sodium hydroxide or potassium hydroxide, according to the following reaction scheme.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: May 6, 1997
    Assignee: Yukong Limited
    Inventors: Taesoo Kwon, Francis J. Taplin
  • Patent number: 5627300
    Abstract: There are disclosed 3-thiocarbamoyl-2-phenyl-1,3-propandiol carbamate racemate, represented by the following structural formula I: ##STR1## and its (R)- and (S)- optical isomers and intermediates thereof, which are very effective for prophylaxis and treatment of central nervous system disorders including epilepsy and apoplexy. 3-Thiocarbamoyl-2-phenyl-1,3-propandiol carbamate racemate and its (S)- and (R)- optical isomers are prepared from 2-phenyl-1,3-propandiol monothiocarbamate, (S)-2-phenyl-1,3-propandiol monothiocarbamate, and (S)-2-phenyl-1,3-propandiol monocarbamate, respectively.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: May 6, 1997
    Assignee: Yukong Limited
    Inventors: Yong M. Choi, Dong I. Han, Hyung C. Kim